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The discovery of novel 8-azabicyclo[3.2.1]octan-3-yl)-3-(4-chlorophenyl) propanamides as vasopressin V1A receptor antagonists.
Bioorg Med Chem Lett. 2011 May 15;21(10):3163-7. doi: 10.1016/j.bmcl.2011.02.096. Epub 2011 Mar 4.
Bioorg Med Chem Lett. 2011.
PMID: 21458261
Discovery and optimisation of a selective non-steroidal glucocorticoid receptor antagonist.
Brown AR, Bosies M, Cameron H, Clark J, Cowley A, Craighead M, Elmore MA, Firth A, Goodwin R, Goutcher S, Grant E, Grassie M, Grove SJ, Hamilton NM, Hampson H, Hillier A, Ho KK, Kiczun M, Kingsbury C, Kultgen SG, Littlewood PT, Lusher SJ, Macdonald S, McIntosh L, McIntyre T, Mistry A, Morphy JR, Nimz O, Ohlmeyer M, Pick J, Rankovic Z, Sherborne B, Smith A, Speake M, Spinks G, Thomson F, Watson L, Weston M.
Brown AR, et al. Among authors: goutcher s.
Bioorg Med Chem Lett. 2011 Jan 1;21(1):137-40. doi: 10.1016/j.bmcl.2010.11.054. Epub 2010 Nov 16.
Bioorg Med Chem Lett. 2011.
PMID: 21129964
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Optimisation of pharmacokinetic properties to afford an orally bioavailable and selective V1A receptor antagonist.
Arbuckle W, Baker J, Barn D, Bingham M, Brown A, Buchanan K, Craighead M, Goodwin R, Goutcher S, Kiczun M, Lyons A, Milne R, Montgomery B, Napier S, Presland J, Sloan H, Turnbull Z, Wishart G.
Arbuckle W, et al. Among authors: goutcher s.
Bioorg Med Chem Lett. 2011 Aug 1;21(15):4622-8. doi: 10.1016/j.bmcl.2011.05.092. Epub 2011 May 30.
Bioorg Med Chem Lett. 2011.
PMID: 21700453
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Role of certain virulence factors in a murine model of Staphylococcus aureus arthritis.
Gemmell CG, Goutcher SC, Reid R, Sturrock RD.
Gemmell CG, et al. Among authors: goutcher sc.
J Med Microbiol. 1997 Mar;46(3):208-13. doi: 10.1099/00222615-46-3-208.
J Med Microbiol. 1997.
PMID: 9126821
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Persistence of Staphylococcus aureus as detected by polymerase chain reaction in the synovial fluid of a patient with septic arthritis.
Canvin JM, Goutcher SC, Hagig M, Gemmell CG, Sturrock RD.
Canvin JM, et al. Among authors: goutcher sc.
Br J Rheumatol. 1997 Feb;36(2):203-6. doi: 10.1093/rheumatology/36.2.203.
Br J Rheumatol. 1997.
PMID: 9133930
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