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The discovery of novel 8-azabicyclo[3.2.1]octan-3-yl)-3-(4-chlorophenyl) propanamides as vasopressin V1A receptor antagonists.
Bioorg Med Chem Lett. 2011 May 15;21(10):3163-7. doi: 10.1016/j.bmcl.2011.02.096. Epub 2011 Mar 4.
Bioorg Med Chem Lett. 2011.
PMID: 21458261
Optimisation of pharmacokinetic properties to afford an orally bioavailable and selective V1A receptor antagonist.
Arbuckle W, Baker J, Barn D, Bingham M, Brown A, Buchanan K, Craighead M, Goodwin R, Goutcher S, Kiczun M, Lyons A, Milne R, Montgomery B, Napier S, Presland J, Sloan H, Turnbull Z, Wishart G.
Arbuckle W, et al. Among authors: barn d.
Bioorg Med Chem Lett. 2011 Aug 1;21(15):4622-8. doi: 10.1016/j.bmcl.2011.05.092. Epub 2011 May 30.
Bioorg Med Chem Lett. 2011.
PMID: 21700453
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The discovery of novel indole-2-carboxamides as cannabinoid CB(1) receptor antagonists.
Cowley PM, Baker J, Barn DR, Buchanan KI, Carlyle I, Clark JK, Clarkson TR, Deehan M, Edwards D, Goodwin RR, Jaap D, Kiyoi Y, Mort C, Palin R, Prosser A, Walker G, Ward N, Wishart G, Young T.
Cowley PM, et al. Among authors: barn dr.
Bioorg Med Chem Lett. 2011 Jan 1;21(1):497-501. doi: 10.1016/j.bmcl.2010.10.104. Epub 2010 Oct 26.
Bioorg Med Chem Lett. 2011.
PMID: 21075628
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Synthesis and SAR studies of 3-phenoxypropyl piperidine analogues as ORL1 (NOP) receptor agonists.
Palin R, Barn DR, Clark JK, Cottney JE, Cowley PM, Crockatt M, Evans L, Feilden H, Goodwin RR, Griekspoor F, Grove SJ, Houghton AK, Jones PS, Morphy RJ, Smith AR, Sundaram H, Vrolijk D, Weston MA, Wishart G, Wren P.
Palin R, et al. Among authors: barn dr.
Bioorg Med Chem Lett. 2005 Feb 1;15(3):589-93. doi: 10.1016/j.bmcl.2004.11.049.
Bioorg Med Chem Lett. 2005.
PMID: 15664818
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Parallel synthesis and biological activity of a new class of high affinity and selective delta-opioid ligand.
Barn DR, Caulfield WL, Cottney J, McGurk K, Morphy JR, Rankovic Z, Roberts B.
Barn DR, et al.
Bioorg Med Chem. 2001 Oct;9(10):2609-24. doi: 10.1016/s0968-0896(01)00017-7.
Bioorg Med Chem. 2001.
PMID: 11557349
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Synthesis of novel analogues of the delta opioid ligand SNC-80 using AlCl3-promoted aminolysis.
Barn DR, Bom A, Cottney J, Caulfield WL, Morphy JR.
Barn DR, et al.
Bioorg Med Chem Lett. 1999 May 3;9(9):1329-34. doi: 10.1016/s0960-894x(99)00174-2.
Bioorg Med Chem Lett. 1999.
PMID: 10340623
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Design and synthesis of a maximally diverse and druglike screening library using REM resin methodology.
Barn D, Caulfield W, Cowley P, Dickins R, Bakker WI, McGuire R, Morphy JR, Rankovic Z, Thorn M.
Barn D, et al.
J Comb Chem. 2001 Nov-Dec;3(6):534-41. doi: 10.1021/cc000096t.
J Comb Chem. 2001.
PMID: 11703148
Item in Clipboard
Solid-phase synthesis of cyclic imides.
Barn DR, Morphy JR.
Barn DR, et al.
J Comb Chem. 1999 Mar-Apr;1(2):151-6. doi: 10.1021/cc980024q.
J Comb Chem. 1999.
PMID: 10746011
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