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Pharmacokinetic, pharmacodynamic, efficacy, and safety data from two randomized, double-blind studies in patients with asthma and an in vitro study comparing two dry-powder inhalers delivering a combination of salmeterol 50 microg and fluticasone propionate 250 microg: implications for establishing bioequivalence of inhaled products.
Daley-Yates PT, Parkins DA, Thomas MJ, Gillett B, House KW, Ortega HG. Daley-Yates PT, et al. Clin Ther. 2009 Feb;31(2):370-85. doi: 10.1016/j.clinthera.2009.02.007. Clin Ther. 2009. PMID: 19302910
Single-dose and steady-state pharmacokinetic and pharmacodynamic evaluation of therapeutically clinically equivalent doses of inhaled fluticasone propionate and budesonide, given as Diskus or Turbohaler dry-powder inhalers to healthy subjects.
Möllmann H, Wagner M, Krishnaswami S, Dimova H, Tang Y, Falcoz C, Daley-Yates PT, Krieg M, Stöckmann R, Barth J, Lawlor C, Möllmann AC, Derendorf H, Hochhaus G. Möllmann H, et al. J Clin Pharmacol. 2001 Dec;41(12):1329-38. doi: 10.1177/00912700122012913. J Clin Pharmacol. 2001. PMID: 11762560 Clinical Trial.
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