Kushida H - Search Results

1

The blood-brain barrier permeability of geissoschizine methyl ether in Uncaria hook, a galenical constituent of the traditional Japanese medicine yokukansan.

Imamura S, Tabuchi M, Kushida H, Nishi A, Kanno H, Yamaguchi T, Sekiguchi K, Ikarashi Y, Kase Y. Imamura S, et al. Among authors: kushida h. Cell Mol Neurobiol. 2011 Jul;31(5):787-93. doi: 10.1007/s10571-011-9676-3. Epub 2011 Mar 26. Cell Mol Neurobiol. 2011. PMID: 21442303

2

Simultaneous quantitative analyses of indole and oxindole alkaloids of Uncaria Hook in rat plasma and brain after oral administration of the traditional Japanese medicine Yokukansan using high-performance liquid chromatography with tandem mass spectrometry.

Kushida H, Fukutake M, Tabuchi M, Katsuhara T, Nishimura H, Ikarashi Y, Kanitani M, Kase Y. Kushida H, et al. Biomed Chromatogr. 2013 Dec;27(12):1647-56. doi: 10.1002/bmc.2974. Epub 2013 Jul 1. Biomed Chromatogr. 2013. PMID: 23813572

3

Specific binding and characteristics of geissoschizine methyl ether, an indole alkaloid of Uncaria Hook, in the rat brain.

Mizoguchi K, Kushida H, Kanno H, Igarashi Y, Nishimura H, Ikarashi Y, Kase Y. Mizoguchi K, et al. Among authors: kushida h. J Ethnopharmacol. 2014 Dec 2;158 Pt A:264-70. doi: 10.1016/j.jep.2014.10.015. Epub 2014 Oct 31. J Ethnopharmacol. 2014. PMID: 25456433

4

Gender differences in plasma pharmacokinetics and hepatic metabolism of geissoschizine methyl ether from Uncaria hook in rats.

Kushida H, Matsumoto T, Ikarashi Y, Nishimura H, Yamamoto M. Kushida H, et al. J Ethnopharmacol. 2021 Jan 10;264:113354. doi: 10.1016/j.jep.2020.113354. Epub 2020 Sep 6. J Ethnopharmacol. 2021. PMID: 32898626 Free article.

5

Metabolic profiling of the Uncaria hook alkaloid geissoschizine methyl ether in rat and human liver microsomes using high-performance liquid chromatography with tandem mass spectrometry.

Kushida H, Matsumoto T, Igarashi Y, Nishimura H, Watanabe J, Maemura K, Kase Y. Kushida H, et al. Molecules. 2015 Jan 27;20(2):2100-14. doi: 10.3390/molecules20022100. Molecules. 2015. PMID: 25633336 Free PMC article.

6

In vitro identification of human cytochrome P450 isoforms involved in the metabolism of Geissoschizine methyl ether, an active component of the traditional Japanese medicine Yokukansan.

Matsumoto T, Kushida H, Maruyama T, Nishimura H, Watanabe J, Maemura K, Kase Y. Matsumoto T, et al. Among authors: kushida h. Xenobiotica. 2016;46(4):325-34. doi: 10.3109/00498254.2015.1076585. Epub 2015 Sep 4. Xenobiotica. 2016. PMID: 26337900

7

In Vivo Pharmacokinetic Analysis Utilizing Non-Targeted and Targeted Mass Spectrometry and In Vitro Assay against Transient Receptor Potential Channels of Maobushisaishinto and Its Constituent Asiasari Radix.

Matsumoto T, Takiyama M, Sanechika S, Nakayama A, Aoki K, Ohbuchi K, Kushida H, Kanno H, Nishi A, Watanabe J. Matsumoto T, et al. Among authors: kushida h. Molecules. 2020 Sep 18;25(18):4283. doi: 10.3390/molecules25184283. Molecules. 2020. PMID: 32962000 Free PMC article.

8

Properties, Pharmacology, and Pharmacokinetics of Active Indole and Oxindole Alkaloids in Uncaria Hook.

Kushida H, Matsumoto T, Ikarashi Y. Kushida H, et al. Front Pharmacol. 2021 Jul 14;12:688670. doi: 10.3389/fphar.2021.688670. eCollection 2021. Front Pharmacol. 2021. PMID: 34335255 Free PMC article. Review.

9

Effects of shakuyakukanzoto and its absorbed components on twitch contractions induced by physiological Ca2+ release in rat skeletal muscle.

Kaifuchi N, Omiya Y, Kushida H, Fukutake M, Nishimura H, Kase Y. Kaifuchi N, et al. Among authors: kushida h. J Nat Med. 2015 Jul;69(3):287-95. doi: 10.1007/s11418-015-0890-z. Epub 2015 Mar 18. J Nat Med. 2015. PMID: 25783410 Free PMC article.

10

Distribution Analysis via Mass Spectrometry Imaging of Ephedrine in the Lungs of Rats Orally Administered the Japanese Kampo Medicine Maoto.

Matsumoto T, Kushida H, Matsushita S, Oyama Y, Suda T, Watanabe J, Kase Y, Setou M. Matsumoto T, et al. Among authors: kushida h. Sci Rep. 2017 Mar 8;7:44098. doi: 10.1038/srep44098. Sci Rep. 2017. PMID: 28272490 Free PMC article.

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