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The epigenetic modifier PRDM5 functions as a tumor suppressor through modulating WNT/β-catenin signaling and is frequently silenced in multiple tumors.
Shu XS, Geng H, Li L, Ying J, Ma C, Wang Y, Poon FF, Wang X, Ying Y, Yeo W, Srivastava G, Tsao SW, Yu J, Sung JJ, Huang S, Chan AT, Tao Q. Shu XS, et al. Among authors: tao q. PLoS One. 2011;6(11):e27346. doi: 10.1371/journal.pone.0027346. Epub 2011 Nov 8. PLoS One. 2011. PMID: 22087297 Free PMC article.
A novel tumor suppressor encoded by a 1p36.3 lncRNA functions as a phosphoinositide-binding protein repressing AKT phosphorylation/activation and promoting autophagy.
Li L, Shu XS, Geng H, Ying J, Guo L, Luo J, Xiang T, Wu L, Ma BBY, Chan ATC, Zhu X, Ambinder RF, Tao Q. Li L, et al. Among authors: tao q. Cell Death Differ. 2023 May;30(5):1166-1183. doi: 10.1038/s41418-023-01129-w. Epub 2023 Feb 23. Cell Death Differ. 2023. PMID: 36813924 Free PMC article.
Epigenetic silencing of a proapoptotic cell adhesion molecule, the immunoglobulin superfamily member IGSF4, by promoter CpG methylation protects Hodgkin lymphoma cells from apoptosis.
Murray PG, Fan Y, Davies G, Ying J, Geng H, Ng KM, Li H, Gao Z, Wei W, Bose S, Anderton J, Kapatai G, Reynolds G, Ito A, Marafioti T, Woodman CB, Ambinder R, Tao Q. Murray PG, et al. Among authors: tao q. Am J Pathol. 2010 Sep;177(3):1480-90. doi: 10.2353/ajpath.2010.100052. Epub 2010 Aug 13. Am J Pathol. 2010. PMID: 20709797 Free PMC article.
1,774 results