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Actinohivin, a broadly neutralizing prokaryotic lectin, inhibits HIV-1 infection by specifically targeting high-mannose-type glycans on the gp120 envelope.
Hoorelbeke B, Huskens D, Férir G, François KO, Takahashi A, Van Laethem K, Schols D, Tanaka H, Balzarini J. Hoorelbeke B, et al. Among authors: balzarini j. Antimicrob Agents Chemother. 2010 Aug;54(8):3287-301. doi: 10.1128/AAC.00254-10. Epub 2010 May 24. Antimicrob Agents Chemother. 2010. PMID: 20498311 Free PMC article.
Mannose-specific plant lectins from the Amaryllidaceae family qualify as efficient microbicides for prevention of human immunodeficiency virus infection.
Balzarini J, Hatse S, Vermeire K, Princen K, Aquaro S, Perno CF, De Clercq E, Egberink H, Vanden Mooter G, Peumans W, Van Damme E, Schols D. Balzarini J, et al. Antimicrob Agents Chemother. 2004 Oct;48(10):3858-70. doi: 10.1128/AAC.48.10.3858-3870.2004. Antimicrob Agents Chemother. 2004. PMID: 15388446 Free PMC article.
Carbohydrate-binding agents cause deletions of highly conserved glycosylation sites in HIV GP120: a new therapeutic concept to hit the achilles heel of HIV.
Balzarini J, Van Laethem K, Hatse S, Froeyen M, Peumans W, Van Damme E, Schols D. Balzarini J, et al. J Biol Chem. 2005 Dec 9;280(49):41005-14. doi: 10.1074/jbc.M508801200. Epub 2005 Sep 23. J Biol Chem. 2005. PMID: 16183648 Free article.
Hippeastrum hybrid and Galanthus nivalis agglutinin) or prokaryotes (i.e. cyanovirin-N) inhibit human immunodeficiency virus (HIV) replication and select for drug-resistant viruses that show profound deletion of N-glycosylation sites in the GP120 envelope (Balzarini, J …
Hippeastrum hybrid and Galanthus nivalis agglutinin) or prokaryotes (i.e. cyanovirin-N) inhibit human immunodeficiency virus (HIV) replicati …
1,242 results