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A novel class of dual mPGES-1/5-LO inhibitors based on the α-naphthyl pirinixic acid scaffold.
Bioorg Med Chem Lett. 2011 Mar 1;21(5):1329-33. doi: 10.1016/j.bmcl.2011.01.049. Epub 2011 Jan 18.
Bioorg Med Chem Lett. 2011.
PMID: 21310608
Rational design of a pirinixic acid derivative that acts as subtype-selective PPARgamma modulator.
Thieme TM, Steri R, Proschak E, Paulke A, Schneider G, Schubert-Zsilavecz M.
Thieme TM, et al.
Bioorg Med Chem Lett. 2010 Apr 15;20(8):2469-73. doi: 10.1016/j.bmcl.2010.03.008. Epub 2010 Mar 4.
Bioorg Med Chem Lett. 2010.
PMID: 20307981
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Synthesis and pharmacological characterization of benzenesulfonamides as dual species inhibitors of human and murine mPGES-1.
Hanke T, Rörsch F, Thieme TM, Ferreiros N, Schneider G, Geisslinger G, Proschak E, Grösch S, Schubert-Zsilavecz M.
Hanke T, et al. Among authors: thieme tm.
Bioorg Med Chem. 2013 Dec 15;21(24):7874-83. doi: 10.1016/j.bmc.2013.10.006. Epub 2013 Oct 16.
Bioorg Med Chem. 2013.
PMID: 24183739
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