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Synthesis and biological evaluation of 1,4-benzodiazepin-2-ones with antitrypanosomal activity.
Bioorg Med Chem. 2011 Mar 1;19(5):1802-15. doi: 10.1016/j.bmc.2011.01.010. Epub 2011 Jan 14.
Bioorg Med Chem. 2011.
PMID: 21306904
1,4-Benzodiazepin-2-ones in medicinal chemistry.
Spencer J, Rathnam RP, Chowdhry BZ.
Spencer J, et al. Among authors: rathnam rp.
Future Med Chem. 2010 Sep;2(9):1441-9. doi: 10.4155/fmc.10.226.
Future Med Chem. 2010.
PMID: 21426139
Review.
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Identification and development of the 1,4-benzodiazepin-2-one and quinazoline-2,4-dione scaffolds as submicromolar inhibitors of HAT.
Clark RL, Clements CJ, Barrett MP, Mackay SP, Rathnam RP, Owusu-Dapaah G, Spencer J, Huggan JK.
Clark RL, et al. Among authors: rathnam rp.
Bioorg Med Chem. 2012 Oct 15;20(20):6019-33. doi: 10.1016/j.bmc.2012.08.049. Epub 2012 Aug 31.
Bioorg Med Chem. 2012.
PMID: 22985960
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Synthesis of a 1,4-benzodiazepine containing palladacycle with in vitro anticancer and cathepsin B activity.
Spencer J, Rathnam RP, Motukuri M, Kotha AK, Richardson SC, Hazrati A, Hartley JA, Male L, Hursthouse MB.
Spencer J, et al. Among authors: rathnam rp.
Dalton Trans. 2009 Jun 14;(22):4299-303. doi: 10.1039/b819061e. Epub 2009 Jan 29.
Dalton Trans. 2009.
PMID: 19662306
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Excellent correlation between cathepsin B inhibition and cytotoxicity for a series of palladacycles.
Spencer J, Casini A, Zava O, Rathnam RP, Velhanda SK, Pfeffer M, Callear SK, Hursthouse MB, Dyson PJ.
Spencer J, et al. Among authors: rathnam rp.
Dalton Trans. 2009 Dec 28;(48):10731-5. doi: 10.1039/b912096c. Epub 2009 Aug 24.
Dalton Trans. 2009.
PMID: 20023902
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Comparison of the safety information on drug labels in three developed countries: The USA, UK and Canada.
Alshammari TM, Devadasu VR, Rathnam RP.
Alshammari TM, et al. Among authors: rathnam rp.
Saudi Pharm J. 2017 Dec;25(8):1103-1107. doi: 10.1016/j.jsps.2017.07.006. Epub 2017 Jul 11.
Saudi Pharm J. 2017.
PMID: 30166896
Free PMC article.
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