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Identifying inhibitors of the Leishmania inositol phosphorylceramide synthase with antiprotozoal activity using a yeast-based assay and ultra-high throughput screening platform.
Norcliffe JL, Mina JG, Alvarez E, Cantizani J, de Dios-Anton F, Colmenarejo G, Valle SG, Marco M, Fiandor JM, Martin JJ, Steel PG, Denny PW. Norcliffe JL, et al. Among authors: mina jg. Sci Rep. 2018 Mar 2;8(1):3938. doi: 10.1038/s41598-018-22063-9. Sci Rep. 2018. PMID: 29500420 Free PMC article.
Tamoxifen inhibits the biosynthesis of inositolphosphorylceramide in Leishmania.
Trinconi CT, Miguel DC, Silber AM, Brown C, Mina JGM, Denny PW, Heise N, Uliana SRB. Trinconi CT, et al. Among authors: mina jgm. Int J Parasitol Drugs Drug Resist. 2018 Dec;8(3):475-487. doi: 10.1016/j.ijpddr.2018.10.007. Epub 2018 Oct 24. Int J Parasitol Drugs Drug Resist. 2018. PMID: 30399513 Free PMC article.
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