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Intestinal DGAT1 deficiency reduces postprandial triglyceride and retinyl ester excursions by inhibiting chylomicron secretion and delaying gastric emptying.
Ables GP, Yang KJ, Vogel S, Hernandez-Ono A, Yu S, Yuen JJ, Birtles S, Buckett LK, Turnbull AV, Goldberg IJ, Blaner WS, Huang LS, Ginsberg HN. Ables GP, et al. Among authors: yu s. J Lipid Res. 2012 Nov;53(11):2364-79. doi: 10.1194/jlr.M029041. Epub 2012 Aug 21. J Lipid Res. 2012. PMID: 22911105 Free PMC article.
Cardiomyocyte lipids impair β-adrenergic receptor function via PKC activation.
Drosatos K, Bharadwaj KG, Lymperopoulos A, Ikeda S, Khan R, Hu Y, Agarwal R, Yu S, Jiang H, Steinberg SF, Blaner WS, Koch WJ, Goldberg IJ. Drosatos K, et al. Among authors: yu s. Am J Physiol Endocrinol Metab. 2011 Mar;300(3):E489-99. doi: 10.1152/ajpendo.00569.2010. Epub 2010 Dec 7. Am J Physiol Endocrinol Metab. 2011. PMID: 21139071 Free PMC article.
Ventricular assist device implantation corrects myocardial lipotoxicity, reverses insulin resistance, and normalizes cardiac metabolism in patients with advanced heart failure.
Chokshi A, Drosatos K, Cheema FH, Ji R, Khawaja T, Yu S, Kato T, Khan R, Takayama H, Knöll R, Milting H, Chung CS, Jorde U, Naka Y, Mancini DM, Goldberg IJ, Schulze PC. Chokshi A, et al. Among authors: yu s. Circulation. 2012 Jun 12;125(23):2844-53. doi: 10.1161/CIRCULATIONAHA.111.060889. Epub 2012 May 14. Circulation. 2012. PMID: 22586279 Free PMC article.
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