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Prime editing functionally corrects cystic fibrosis-causing CFTR mutations in human organoids and airway epithelial cells.
Bulcaen M, Kortleven P, Liu RB, Maule G, Dreano E, Kelly M, Ensinck MM, Thierie S, Smits M, Ciciani M, Hatton A, Chevalier B, Ramalho AS, Casadevall I Solvas X, Debyser Z, Vermeulen F, Gijsbers R, Sermet-Gaudelus I, Cereseto A, Carlon MS. Bulcaen M, et al. Among authors: carlon ms. Cell Rep Med. 2024 May 21;5(5):101544. doi: 10.1016/j.xcrm.2024.101544. Epub 2024 May 1. Cell Rep Med. 2024. PMID: 38697102 Free article.
Genetic surgery for a cystic fibrosis-causing splicing mutation.
Bulcaen M, Carlon MS. Bulcaen M, et al. Among authors: carlon ms. Mol Ther Methods Clin Dev. 2024 Jan 2;32(1):101177. doi: 10.1016/j.omtm.2023.101177. eCollection 2024 Mar 14. Mol Ther Methods Clin Dev. 2024. PMID: 38261927 Free PMC article. No abstract available.
Unagi: Deep Generative Model for Deciphering Cellular Dynamics and In-Silico Drug Discovery in Complex Diseases.
Zheng Y, Schupp JC, Adams T, Clair G, Justet A, Ahangari F, Yan X, Hansen P, Carlon M, Cortesi E, Vermant M, Vos R, De Sadeleer LJ, Rosas IO, Pineda R, Sembrat J, Königshoff M, McDonough JE, Vanaudenaerde BM, Wuyts WA, Kaminski N, Ding J. Zheng Y, et al. Among authors: carlon m. Res Sq [Preprint]. 2023 Dec 18:rs.3.rs-3676579. doi: 10.21203/rs.3.rs-3676579/v1. Res Sq. 2023. PMID: 38196613 Free PMC article. Preprint.
Intrafamilial Correlation and Variability in the Clinical Evolution of Pulmonary Fibrosis.
Goos T, Dubbeldam A, Vermant M, Gogaert S, De Sadeleer LJ, De Crem N, De Langhe E, Yserbyt J, Weynand B, Carlon MS, Verschakelen J, Vermeer S, Verleden SE, Wuyts WA. Goos T, et al. Among authors: carlon ms. Chest. 2023 Dec;164(6):1476-1480. doi: 10.1016/j.chest.2023.07.003. Epub 2023 Jul 10. Chest. 2023. PMID: 37437878 Free article. No abstract available.
Nanoblades allow high-level genome editing in murine and human organoids.
Tiroille V, Krug A, Bokobza E, Kahi M, Bulcaen M, Ensinck MM, Geurts MH, Hendriks D, Vermeulen F, Larbret F, Gutierrez-Guerrero A, Chen Y, Van Zundert I, Rocha S, Rios AC, Medaer L, Gijsbers R, Mangeot PE, Clevers H, Carlon MS, Bost F, Verhoeyen E. Tiroille V, et al. Among authors: carlon ms. Mol Ther Nucleic Acids. 2023 Jun 8;33:57-74. doi: 10.1016/j.omtn.2023.06.004. eCollection 2023 Sep 12. Mol Ther Nucleic Acids. 2023. PMID: 37435135 Free PMC article.
Severity of the S1251N allele in cystic fibrosis is affected by the presence of the F508C variant in cis.
Cuyx S, Ramalho SS, Callebaut I, Cuppens H, Kmit A, Arnauts K, Ferrante M, Verfaillie C, Ensinck M, Carlon MS, Boon M, Proesmans M, Dupont L, De Boeck K, Farinha CM, Vermeulen F, Ramalho AS. Cuyx S, et al. Among authors: carlon ms. J Cyst Fibros. 2022 Jul;21(4):644-651. doi: 10.1016/j.jcf.2022.05.013. Epub 2022 Jun 9. J Cyst Fibros. 2022. PMID: 35690578
57 results