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Functional overlap and regulatory links shape genetic interactions between signaling pathways.
van Wageningen S, Kemmeren P, Lijnzaad P, Margaritis T, Benschop JJ, de Castro IJ, van Leenen D, Groot Koerkamp MJ, Ko CW, Miles AJ, Brabers N, Brok MO, Lenstra TL, Fiedler D, Fokkens L, Aldecoa R, Apweiler E, Taliadouros V, Sameith K, van de Pasch LA, van Hooff SR, Bakker LV, Krogan NJ, Snel B, Holstege FC. van Wageningen S, et al. Among authors: van de pasch la, van leenen d, van hooff sr. Cell. 2010 Dec 10;143(6):991-1004. doi: 10.1016/j.cell.2010.11.021. Cell. 2010. PMID: 21145464 Free PMC article.
A consensus of core protein complex compositions for Saccharomyces cerevisiae.
Benschop JJ, Brabers N, van Leenen D, Bakker LV, van Deutekom HW, van Berkum NL, Apweiler E, Lijnzaad P, Holstege FC, Kemmeren P. Benschop JJ, et al. Among authors: van deutekom hw, van leenen d, van berkum nl. Mol Cell. 2010 Jun 25;38(6):916-28. doi: 10.1016/j.molcel.2010.06.002. Mol Cell. 2010. PMID: 20620961 Free article.
The specificity and topology of chromatin interaction pathways in yeast.
Lenstra TL, Benschop JJ, Kim T, Schulze JM, Brabers NA, Margaritis T, van de Pasch LA, van Heesch SA, Brok MO, Groot Koerkamp MJ, Ko CW, van Leenen D, Sameith K, van Hooff SR, Lijnzaad P, Kemmeren P, Hentrich T, Kobor MS, Buratowski S, Holstege FC. Lenstra TL, et al. Among authors: van heesch sa, van de pasch la, van leenen d, van hooff sr. Mol Cell. 2011 May 20;42(4):536-49. doi: 10.1016/j.molcel.2011.03.026. Mol Cell. 2011. PMID: 21596317 Free PMC article.
Large-scale genetic perturbations reveal regulatory networks and an abundance of gene-specific repressors.
Kemmeren P, Sameith K, van de Pasch LA, Benschop JJ, Lenstra TL, Margaritis T, O'Duibhir E, Apweiler E, van Wageningen S, Ko CW, van Heesch S, Kashani MM, Ampatziadis-Michailidis G, Brok MO, Brabers NA, Miles AJ, Bouwmeester D, van Hooff SR, van Bakel H, Sluiters E, Bakker LV, Snel B, Lijnzaad P, van Leenen D, Groot Koerkamp MJ, Holstege FC. Kemmeren P, et al. Among authors: van leenen d. Cell. 2014 Apr 24;157(3):740-52. doi: 10.1016/j.cell.2014.02.054. Cell. 2014. PMID: 24766815 Free article.
A high-resolution gene expression atlas of epistasis between gene-specific transcription factors exposes potential mechanisms for genetic interactions.
Sameith K, Amini S, Groot Koerkamp MJ, van Leenen D, Brok M, Brabers N, Lijnzaad P, van Hooff SR, Benschop JJ, Lenstra TL, Apweiler E, van Wageningen S, Snel B, Holstege FC, Kemmeren P. Sameith K, et al. Among authors: van leenen d. BMC Biol. 2015 Dec 23;13:112. doi: 10.1186/s12915-015-0222-5. BMC Biol. 2015. PMID: 26700642 Free PMC article.
Two distinct repressive mechanisms for histone 3 lysine 4 methylation through promoting 3'-end antisense transcription.
Margaritis T, Oreal V, Brabers N, Maestroni L, Vitaliano-Prunier A, Benschop JJ, van Hooff S, van Leenen D, Dargemont C, Géli V, Holstege FC. Margaritis T, et al. Among authors: van hooff s, van leenen d. PLoS Genet. 2012 Sep;8(9):e1002952. doi: 10.1371/journal.pgen.1002952. Epub 2012 Sep 20. PLoS Genet. 2012. PMID: 23028359 Free PMC article.
Balancing of histone H3K4 methylation states by the Kdm5c/SMCX histone demethylase modulates promoter and enhancer function.
Outchkourov NS, Muiño JM, Kaufmann K, van Ijcken WF, Groot Koerkamp MJ, van Leenen D, de Graaf P, Holstege FC, Grosveld FG, Timmers HT. Outchkourov NS, et al. Among authors: van ijcken wf, van leenen d. Cell Rep. 2013 Apr 25;3(4):1071-9. doi: 10.1016/j.celrep.2013.02.030. Epub 2013 Mar 28. Cell Rep. 2013. PMID: 23545502 Free article.
47 results