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Design, synthesis and biological evaluation of benzo[e][1,2,4]triazin-7(1H)-one and [1,2,4]-triazino[5,6,1-jk]carbazol-6-one derivatives as dual inhibitors of beta-amyloid aggregation and acetyl/butyryl cholinesterase.
Catto M, Berezin AA, Lo Re D, Loizou G, Demetriades M, De Stradis A, Campagna F, Koutentis PA, Carotti A. Catto M, et al. Among authors: campagna f. Eur J Med Chem. 2012 Dec;58:84-97. doi: 10.1016/j.ejmech.2012.10.003. Epub 2012 Oct 11. Eur J Med Chem. 2012. PMID: 23108363
1,3-Dialkyl-8-(hetero)aryl-9-OH-9-deazaxanthines as potent A2B adenosine receptor antagonists: design, synthesis, structure-affinity and structure-selectivity relationships.
Stefanachi A, Nicolotti O, Leonetti F, Cellamare S, Campagna F, Loza MI, Brea JM, Mazza F, Gavuzzo E, Carotti A. Stefanachi A, et al. Among authors: campagna f. Bioorg Med Chem. 2008 Nov 15;16(22):9780-9. doi: 10.1016/j.bmc.2008.09.067. Epub 2008 Sep 30. Bioorg Med Chem. 2008. PMID: 18938084
Mannich base approach to 5-methoxyisatin 3-(4-isopropylphenyl)hydrazone: A water-soluble prodrug for a multitarget inhibition of cholinesterases, beta-amyloid fibrillization and oligomer-induced cytotoxicity.
Pisani L, De Palma A, Giangregorio N, Miniero DV, Pesce P, Nicolotti O, Campagna F, Altomare CD, Catto M. Pisani L, et al. Among authors: campagna f. Eur J Pharm Sci. 2017 Nov 15;109:381-388. doi: 10.1016/j.ejps.2017.08.004. Epub 2017 Aug 9. Eur J Pharm Sci. 2017. PMID: 28801274
76 results