Chien AJ - Search Results

1

Chemical-genetic screen identifies riluzole as an enhancer of Wnt/β-catenin signaling in melanoma.

Biechele TL, Camp ND, Fass DM, Kulikauskas RM, Robin NC, White BD, Taraska CM, Moore EC, Muster J, Karmacharya R, Haggarty SJ, Chien AJ, Moon RT. Biechele TL, et al. Among authors: chien aj. Chem Biol. 2010 Nov 24;17(11):1177-82. doi: 10.1016/j.chembiol.2010.08.012. Chem Biol. 2010. PMID: 21095567 Free PMC article.

2

CTLA-4 is a direct target of Wnt/beta-catenin signaling and is expressed in human melanoma tumors.

Shah KV, Chien AJ, Yee C, Moon RT. Shah KV, et al. Among authors: chien aj. J Invest Dermatol. 2008 Dec;128(12):2870-9. doi: 10.1038/jid.2008.170. Epub 2008 Jun 19. J Invest Dermatol. 2008. PMID: 18563180 Free PMC article.

3

Activated Wnt/beta-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model.

Chien AJ, Moore EC, Lonsdorf AS, Kulikauskas RM, Rothberg BG, Berger AJ, Major MB, Hwang ST, Rimm DL, Moon RT. Chien AJ, et al. Proc Natl Acad Sci U S A. 2009 Jan 27;106(4):1193-8. doi: 10.1073/pnas.0811902106. Epub 2009 Jan 14. Proc Natl Acad Sci U S A. 2009. PMID: 19144919 Free PMC article.

4

A Wnt survival guide: from flies to human disease.

Chien AJ, Conrad WH, Moon RT. Chien AJ, et al. J Invest Dermatol. 2009 Jul;129(7):1614-27. doi: 10.1038/jid.2008.445. Epub 2009 Jan 29. J Invest Dermatol. 2009. PMID: 19177135 Free PMC article. Review.

5

Wnt/Fz signaling and the cytoskeleton: potential roles in tumorigenesis.

Lai SL, Chien AJ, Moon RT. Lai SL, et al. Among authors: chien aj. Cell Res. 2009 May;19(5):532-45. doi: 10.1038/cr.2009.41. Cell Res. 2009. PMID: 19365405 Review.

6

A re-evaluation of the "oncogenic" nature of Wnt/beta-catenin signaling in melanoma and other cancers.

Lucero OM, Dawson DW, Moon RT, Chien AJ. Lucero OM, et al. Among authors: chien aj. Curr Oncol Rep. 2010 Sep;12(5):314-8. doi: 10.1007/s11912-010-0114-3. Curr Oncol Rep. 2010. PMID: 20603725 Free PMC article. Review.

7

Wnt/β-catenin signaling and AXIN1 regulate apoptosis triggered by inhibition of the mutant kinase BRAFV600E in human melanoma.

Biechele TL, Kulikauskas RM, Toroni RA, Lucero OM, Swift RD, James RG, Robin NC, Dawson DW, Moon RT, Chien AJ. Biechele TL, et al. Among authors: chien aj. Sci Signal. 2012 Jan 10;5(206):ra3. doi: 10.1126/scisignal.2002274. Sci Signal. 2012. PMID: 22234612 Free PMC article.

8

Regulating the response to targeted MEK inhibition in melanoma: enhancing apoptosis in NRAS- and BRAF-mutant melanoma cells with Wnt/β-catenin activation.

Conrad WH, Swift RD, Biechele TL, Kulikauskas RM, Moon RT, Chien AJ. Conrad WH, et al. Among authors: chien aj. Cell Cycle. 2012 Oct 15;11(20):3724-30. doi: 10.4161/cc.21645. Epub 2012 Aug 16. Cell Cycle. 2012. PMID: 22895053 Free PMC article.

9

Activation of Wnt/β-catenin signaling increases apoptosis in melanoma cells treated with trail.

Zimmerman ZF, Kulikauskas RM, Bomsztyk K, Moon RT, Chien AJ. Zimmerman ZF, et al. Among authors: chien aj. PLoS One. 2013 Jul 15;8(7):e69593. doi: 10.1371/journal.pone.0069593. Print 2013. PLoS One. 2013. PMID: 23869245 Free PMC article.

10

Protein kinase PKN1 represses Wnt/β-catenin signaling in human melanoma cells.

James RG, Bosch KA, Kulikauskas RM, Yang PT, Robin NC, Toroni RA, Biechele TL, Berndt JD, von Haller PD, Eng JK, Wolf-Yadlin A, Chien AJ, Moon RT. James RG, et al. Among authors: chien aj. J Biol Chem. 2013 Nov 29;288(48):34658-70. doi: 10.1074/jbc.M113.500314. Epub 2013 Oct 10. J Biol Chem. 2013. PMID: 24114839 Free PMC article.

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