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Macromolecular condensation organizes nucleolar sub-phases to set up a pH gradient.
King MR, Ruff KM, Lin AZ, Pant A, Farag M, Lalmansingh JM, Wu T, Fossat MJ, Ouyang W, Lew MD, Lundberg E, Vahey MD, Pappu RV. King MR, et al. Among authors: ruff km. Cell. 2024 Apr 11;187(8):1889-1906.e24. doi: 10.1016/j.cell.2024.02.029. Epub 2024 Mar 18. Cell. 2024. PMID: 38503281 Free article.
Metastable condensates suppress conversion to amyloid fibrils.
Das T, Zaidi F, Farag M, Ruff KM, Messing J, Taylor JP, Pappu RV, Mittag T. Das T, et al. Among authors: ruff km. bioRxiv [Preprint]. 2024 Mar 3:2024.02.28.582569. doi: 10.1101/2024.02.28.582569. bioRxiv. 2024. PMID: 38464104 Free PMC article. Preprint.
Emergent microenvironments of nucleoli.
King MR, Ruff KM, Pappu RV. King MR, et al. Among authors: ruff km. Nucleus. 2024 Dec;15(1):2319957. doi: 10.1080/19491034.2024.2319957. Epub 2024 Mar 5. Nucleus. 2024. PMID: 38443761 Free PMC article. Review.
Race, racism, and covid-19 in the US: lessons not learnt.
Bentley-Edwards KL, Adisa O, Ruff KE, McClure ES, Robinson WR. Bentley-Edwards KL, et al. Among authors: ruff ke. BMJ. 2024 Feb 26;384:e076106. doi: 10.1136/bmj-2023-076106. BMJ. 2024. PMID: 38408791 No abstract available.
Dynamical control enables the formation of demixed biomolecular condensates.
Lin AZ, Ruff KM, Dar F, Jalihal A, King MR, Lalmansingh JM, Posey AE, Erkamp NA, Seim I, Gladfelter AS, Pappu RV. Lin AZ, et al. Among authors: ruff km. Nat Commun. 2023 Nov 24;14(1):7678. doi: 10.1038/s41467-023-43489-4. Nat Commun. 2023. PMID: 37996438 Free PMC article.
A disordered region controls cBAF activity via condensation and partner recruitment.
Patil A, Strom AR, Paulo JA, Collings CK, Ruff KM, Shinn MK, Sankar A, Cervantes KS, Wauer T, St Laurent JD, Xu G, Becker LA, Gygi SP, Pappu RV, Brangwynne CP, Kadoch C. Patil A, et al. Among authors: ruff km. Cell. 2023 Oct 26;186(22):4936-4955.e26. doi: 10.1016/j.cell.2023.08.032. Epub 2023 Oct 3. Cell. 2023. PMID: 37788668 Free article.
91 results