Charman SA - Search Results

1

Preclinical comparison of intravenous melphalan pharmacokinetics administered in formulations containing either (SBE)7 m-β-cyclodextrin or a co-solvent system.

Koltun M, Morizzi J, Katneni K, Charman SA, Shackleford DM, McIntosh MP. Koltun M, et al. Among authors: charman sa. Biopharm Drug Dispos. 2010 Nov;31(8-9):450-4. doi: 10.1002/bdd.725. Biopharm Drug Dispos. 2010. PMID: 20865695

2

Alteration of the intravenous pharmacokinetics of a synthetic ozonide antimalarial in the presence of a modified cyclodextrin.

Charman SA, Perry CS, Chiu FC, McIntosh KA, Prankerd RJ, Charman WN. Charman SA, et al. Among authors: charman wn. J Pharm Sci. 2006 Feb;95(2):256-67. doi: 10.1002/jps.20534. J Pharm Sci. 2006. PMID: 16374851

3

Permeability assessment of poorly water-soluble compounds under solubilizing conditions: the reciprocal permeability approach.

Katneni K, Charman SA, Porter CJ. Katneni K, et al. Among authors: charman sa. J Pharm Sci. 2006 Oct;95(10):2170-85. doi: 10.1002/jps.20687. J Pharm Sci. 2006. PMID: 16883557

4

Impact of cremophor-EL and polysorbate-80 on digoxin permeability across rat jejunum: delineation of thermodynamic and transporter related events using the reciprocal permeability approach.

Katneni K, Charman SA, Porter CJ. Katneni K, et al. Among authors: charman sa. J Pharm Sci. 2007 Feb;96(2):280-93. doi: 10.1002/jps.20779. J Pharm Sci. 2007. PMID: 17051595

5

Use of plasma proteins as solubilizing agents in in vitro permeability experiments: correction for unbound drug concentration using the reciprocal permeability approach.

Katneni K, Charman SA, Porter CJ. Katneni K, et al. Among authors: charman sa. J Pharm Sci. 2008 Jan;97(1):209-24. doi: 10.1002/jps.20877. J Pharm Sci. 2008. PMID: 17585392

6

Pharmacokinetics and brain uptake of AM-36, a novel neuroprotective agent, following intravenous administration to rats.

Nicolazzo JA, Nguyen TT, Katneni K, Steuten JA, Smith G, Jarrott B, Callaway JK, Charman SA. Nicolazzo JA, et al. Among authors: charman sa. J Pharm Pharmacol. 2008 Feb;60(2):171-8. doi: 10.1211/jpp.60.2.0005. J Pharm Pharmacol. 2008. PMID: 18237464

7

An evaluation of the relative roles of the unstirred water layer and receptor sink in limiting the in-vitro intestinal permeability of drug compounds of varying lipophilicity.

Katneni K, Charman SA, Porter CJ. Katneni K, et al. Among authors: charman sa. J Pharm Pharmacol. 2008 Oct;60(10):1311-9. doi: 10.1211/jpp/60.10.0007. J Pharm Pharmacol. 2008. PMID: 18812024

8

Discovery of CYT997: a structurally novel orally active microtubule targeting agent.

Burns CJ, Harte MF, Bu X, Fantino E, Joffe M, Sikanyika H, Su S, Tranberg CE, Wilson N, Charman SA, Shackleford DM, Wilks AF. Burns CJ, et al. Among authors: charman sa. Bioorg Med Chem Lett. 2009 Aug 15;19(16):4639-42. doi: 10.1016/j.bmcl.2009.06.079. Epub 2009 Jun 25. Bioorg Med Chem Lett. 2009. PMID: 19616947

9

Simultaneous determination of OZ277, a synthetic 1,2,4-trioxolane antimalarial, and its polar metabolites in rat plasma using hydrophilic interaction chromatography.

Bhamidipati RK, Morizzi J, Chiu FC, Shackleford DM, Charman SA. Bhamidipati RK, et al. Among authors: charman sa. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Oct 1;877(27):2989-95. doi: 10.1016/j.jchromb.2009.07.015. Epub 2009 Jul 17. J Chromatogr B Analyt Technol Biomed Life Sci. 2009. PMID: 19646936

10

Phenylaminopyrimidines as inhibitors of Janus kinases (JAKs).

Burns CJ, Bourke DG, Andrau L, Bu X, Charman SA, Donohue AC, Fantino E, Farrugia M, Feutrill JT, Joffe M, Kling MR, Kurek M, Nero TL, Nguyen T, Palmer JT, Phillips I, Shackleford DM, Sikanyika H, Styles M, Su S, Treutlein H, Zeng J, Wilks AF. Burns CJ, et al. Among authors: charman sa. Bioorg Med Chem Lett. 2009 Oct 15;19(20):5887-92. doi: 10.1016/j.bmcl.2009.08.071. Epub 2009 Aug 23. Bioorg Med Chem Lett. 2009. PMID: 19762238

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