Brady T - Search Results

1

Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia.

Cavazzana-Calvo M, Payen E, Negre O, Wang G, Hehir K, Fusil F, Down J, Denaro M, Brady T, Westerman K, Cavallesco R, Gillet-Legrand B, Caccavelli L, Sgarra R, Maouche-Chrétien L, Bernaudin F, Girot R, Dorazio R, Mulder GJ, Polack A, Bank A, Soulier J, Larghero J, Kabbara N, Dalle B, Gourmel B, Socie G, Chrétien S, Cartier N, Aubourg P, Fischer A, Cornetta K, Galacteros F, Beuzard Y, Gluckman E, Bushman F, Hacein-Bey-Abina S, Leboulch P. Cavazzana-Calvo M, et al. Among authors: brady t. Nature. 2010 Sep 16;467(7313):318-22. doi: 10.1038/nature09328. Nature. 2010. PMID: 20844535 Free PMC article.

2

Distribution of lentiviral vector integration sites in mice following therapeutic gene transfer to treat β-thalassemia.

Ronen K, Negre O, Roth S, Colomb C, Malani N, Denaro M, Brady T, Fusil F, Gillet-Legrand B, Hehir K, Beuzard Y, Leboulch P, Down JD, Payen E, Bushman FD. Ronen K, et al. Among authors: brady t. Mol Ther. 2011 Jul;19(7):1273-86. doi: 10.1038/mt.2011.20. Epub 2011 Mar 8. Mol Ther. 2011. PMID: 21386821 Free PMC article.

3

A method to sequence and quantify DNA integration for monitoring outcome in gene therapy.

Brady T, Roth SL, Malani N, Wang GP, Berry CC, Leboulch P, Hacein-Bey-Abina S, Cavazzana-Calvo M, Papapetrou EP, Sadelain M, Savilahti H, Bushman FD. Brady T, et al. Nucleic Acids Res. 2011 Jun;39(11):e72. doi: 10.1093/nar/gkr140. Epub 2011 Mar 16. Nucleic Acids Res. 2011. PMID: 21415009 Free PMC article.

4

Methods for integration site distribution analyses in animal cell genomes.

Ciuffi A, Ronen K, Brady T, Malani N, Wang G, Berry CC, Bushman FD. Ciuffi A, et al. Among authors: brady t. Methods. 2009 Apr;47(4):261-8. doi: 10.1016/j.ymeth.2008.10.028. Epub 2008 Nov 25. Methods. 2009. PMID: 19038346 Free PMC article.

5

Nondividing cells: a safer bet for integrating vectors?

Brady T, Bushman FD. Brady T, et al. Mol Ther. 2011 Apr;19(4):640-1. doi: 10.1038/mt.2011.40. Mol Ther. 2011. PMID: 21455211 Free PMC article. No abstract available.

6

Integration target site selection by a resurrected human endogenous retrovirus.

Brady T, Lee YN, Ronen K, Malani N, Berry CC, Bieniasz PD, Bushman FD. Brady T, et al. Genes Dev. 2009 Mar 1;23(5):633-42. doi: 10.1101/gad.1762309. Genes Dev. 2009. PMID: 19270161 Free PMC article.

7

Quantitation of HIV DNA integration: effects of differential integration site distributions on Alu-PCR assays.

Brady T, Kelly BJ, Male F, Roth S, Bailey A, Malani N, Gijsbers R, O'Doherty U, Bushman FD. Brady T, et al. J Virol Methods. 2013 Apr;189(1):53-7. doi: 10.1016/j.jviromet.2013.01.004. Epub 2013 Jan 21. J Virol Methods. 2013. PMID: 23348058 Free PMC article.

8

HIV integration targeting: a pathway involving Transportin-3 and the nuclear pore protein RanBP2.

Ocwieja KE, Brady TL, Ronen K, Huegel A, Roth SL, Schaller T, James LC, Towers GJ, Young JA, Chanda SK, König R, Malani N, Berry CC, Bushman FD. Ocwieja KE, et al. Among authors: brady tl. PLoS Pathog. 2011 Mar;7(3):e1001313. doi: 10.1371/journal.ppat.1001313. Epub 2011 Mar 10. PLoS Pathog. 2011. PMID: 21423673 Free PMC article.

9

HIV integration site distributions in resting and activated CD4+ T cells infected in culture.

Brady T, Agosto LM, Malani N, Berry CC, O'Doherty U, Bushman F. Brady T, et al. AIDS. 2009 Jul 31;23(12):1461-71. doi: 10.1097/QAD.0b013e32832caf28. AIDS. 2009. PMID: 19550285 Free PMC article.

10

Antiviral effects of autologous CD4 T cells genetically modified with a conditionally replicating lentiviral vector expressing long antisense to HIV.

Tebas P, Stein D, Binder-Scholl G, Mukherjee R, Brady T, Rebello T, Humeau L, Kalos M, Papasavvas E, Montaner LJ, Schullery D, Shaheen F, Brennan AL, Zheng Z, Cotte J, Slepushkin V, Veloso E, Mackley A, Hwang WT, Aberra F, Zhan J, Boyer J, Collman RG, Bushman FD, Levine BL, June CH. Tebas P, et al. Among authors: brady t. Blood. 2013 Feb 28;121(9):1524-33. doi: 10.1182/blood-2012-07-447250. Epub 2012 Dec 20. Blood. 2013. PMID: 23264589 Free PMC article. Clinical Trial.

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