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Classical transient receptor potential channel 6 (TRPC6) is essential for hypoxic pulmonary vasoconstriction and alveolar gas exchange.
Weissmann N, Dietrich A, Fuchs B, Kalwa H, Ay M, Dumitrascu R, Olschewski A, Storch U, Mederos y Schnitzler M, Ghofrani HA, Schermuly RT, Pinkenburg O, Seeger W, Grimminger F, Gudermann T. Weissmann N, et al. Among authors: fuchs b. Proc Natl Acad Sci U S A. 2006 Dec 12;103(50):19093-8. doi: 10.1073/pnas.0606728103. Epub 2006 Dec 1. Proc Natl Acad Sci U S A. 2006. PMID: 17142322 Free PMC article.
Heme oxygenase-2 and large-conductance Ca2+-activated K+ channels: lung vascular effects of hypoxia.
Roth M, Rupp M, Hofmann S, Mittal M, Fuchs B, Sommer N, Parajuli N, Quanz K, Schubert D, Dony E, Schermuly RT, Ghofrani HA, Sausbier U, Rutschmann K, Wilhelm S, Seeger W, Ruth P, Grimminger F, Sausbier M, Weissmann N. Roth M, et al. Among authors: fuchs b. Am J Respir Crit Care Med. 2009 Aug 15;180(4):353-64. doi: 10.1164/rccm.200806-848OC. Epub 2009 Jun 4. Am J Respir Crit Care Med. 2009. PMID: 19498059
Mitochondrial hyperpolarization in pulmonary vascular remodeling. Mitochondrial uncoupling protein deficiency as disease model.
Pak O, Sommer N, Hoeres T, Bakr A, Waisbrod S, Sydykov A, Haag D, Esfandiary A, Kojonazarov B, Veit F, Fuchs B, Weisel FC, Hecker M, Schermuly RT, Grimminger F, Ghofrani HA, Seeger W, Weissmann N. Pak O, et al. Among authors: fuchs b. Am J Respir Cell Mol Biol. 2013 Sep;49(3):358-67. doi: 10.1165/rcmb.2012-0361OC. Am J Respir Cell Mol Biol. 2013. PMID: 23590303
Classical transient receptor potential channel 1 in hypoxia-induced pulmonary hypertension.
Malczyk M, Veith C, Fuchs B, Hofmann K, Storch U, Schermuly RT, Witzenrath M, Ahlbrecht K, Fecher-Trost C, Flockerzi V, Ghofrani HA, Grimminger F, Seeger W, Gudermann T, Dietrich A, Weissmann N. Malczyk M, et al. Among authors: fuchs b. Am J Respir Crit Care Med. 2013 Dec 15;188(12):1451-9. doi: 10.1164/rccm.201307-1252OC. Am J Respir Crit Care Med. 2013. PMID: 24251695
The soluble guanylate cyclase activator HMR1766 reverses hypoxia-induced experimental pulmonary hypertension in mice.
Weissmann N, Hackemack S, Dahal BK, Pullamsetti SS, Savai R, Mittal M, Fuchs B, Medebach T, Dumitrascu R, Eickels Mv, Ghofrani HA, Seeger W, Grimminger F, Schermuly RT. Weissmann N, et al. Among authors: fuchs b. Am J Physiol Lung Cell Mol Physiol. 2009 Oct;297(4):L658-65. doi: 10.1152/ajplung.00189.2009. Epub 2009 Jul 17. Am J Physiol Lung Cell Mol Physiol. 2009. PMID: 19617308 Free article.
967 results