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Syringol isolated from Eleusine coracana (L.) Gaertn bran suppresses inflammatory response through the down-regulation of cPLA2, COX-2, IκBα, p38 and MPO signaling in sPLA2 induced mice paw oedema.
Milan Gowda MD, Jayachandra K, Joshi V, Manjuprasanna VN, Rudresha GV, Velmurugan D, Pachaiappan R, Jameel NM, Vishwanath BS. Milan Gowda MD, et al. Among authors: jameel nm. Inflammopharmacology. 2022 Oct;30(5):1853-1870. doi: 10.1007/s10787-022-00983-3. Epub 2022 May 31. Inflammopharmacology. 2022. PMID: 35639234
Inhibition of sPLA2 enzyme activity by cell-permeable antioxidant EUK-8 and downregulation of p38, Akt, and p65 signals induced by sPLA2 in inflammatory mouse paw edema model.
Jayachandra K, Gowda MDM, Rudresha GV, Manjuprasanna VN, Urs AP, Nandana MB, Bharatha M, Jameel NM, Vishwanath BS. Jayachandra K, et al. Among authors: jameel nm. J Cell Biochem. 2023 Feb;124(2):294-307. doi: 10.1002/jcb.30366. Epub 2022 Dec 31. J Cell Biochem. 2023. PMID: 36585945