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SDHAF1 confers metabolic resilience to aging hematopoietic stem cells by promoting mitochondrial ATP production.
Watanuki S, Kobayashi H, Sugiura Y, Yamamoto M, Karigane D, Shiroshita K, Sorimachi Y, Morikawa T, Fujita S, Shide K, Haraguchi M, Tamaki S, Mikawa T, Kondoh H, Nakano H, Sumiyama K, Nagamatsu G, Goda N, Okamoto S, Nakamura-Ishizu A, Shimoda K, Suematsu M, Suda T, Takubo K. Watanuki S, et al. Among authors: takubo k. Cell Stem Cell. 2024 May 14:S1934-5909(24)00176-0. doi: 10.1016/j.stem.2024.04.023. Online ahead of print. Cell Stem Cell. 2024. PMID: 38772377
Collaboration between a cis-interacting natural killer cell receptor and membrane sphingolipid is critical for the phagocyte function.
Karyu H, Niki T, Sorimachi Y, Hata S, Shimabukuro-Demoto S, Hirabayashi T, Mukai K, Kasahara K, Takubo K, Goda N, Honke K, Taguchi T, Sorimachi H, Toyama-Sorimachi N. Karyu H, et al. Among authors: takubo k. Front Immunol. 2024 Apr 24;15:1401294. doi: 10.3389/fimmu.2024.1401294. eCollection 2024. Front Immunol. 2024. PMID: 38720899 Free PMC article.
Context-dependent modification of PFKFB3 in hematopoietic stem cells promotes anaerobic glycolysis and ensures stress hematopoiesis.
Watanuki S, Kobayashi H, Sugiura Y, Yamamoto M, Karigane D, Shiroshita K, Sorimachi Y, Fujita S, Morikawa T, Koide S, Oshima M, Nishiyama A, Murakami K, Haraguchi M, Tamaki S, Yamamoto T, Yabushita T, Tanaka Y, Nagamatsu G, Honda H, Okamoto S, Goda N, Tamura T, Nakamura-Ishizu A, Suematsu M, Iwama A, Suda T, Takubo K. Watanuki S, et al. Among authors: takubo k. Elife. 2024 Apr 4;12:RP87674. doi: 10.7554/eLife.87674. Elife. 2024. PMID: 38573813 Free PMC article.
Squamous Neoplastic Precursor Lesions of the Esophagus.
Arai T, Ono S, Takubo K. Arai T, et al. Among authors: takubo k. Gastroenterol Clin North Am. 2024 Mar;53(1):25-38. doi: 10.1016/j.gtc.2023.09.004. Epub 2023 Oct 23. Gastroenterol Clin North Am. 2024. PMID: 38280749 Review.
Spatial heterogeneity of bone marrow endothelial cells unveils a distinct subtype in the epiphysis.
Iga T, Kobayashi H, Kusumoto D, Sanosaka T, Fujita N, Tai-Nagara I, Ando T, Takahashi T, Matsuo K, Hozumi K, Ito K, Ema M, Miyamoto T, Matsumoto M, Nakamura M, Okano H, Shibata S, Kohyama J, Kim KK, Takubo K, Kubota Y. Iga T, et al. Among authors: takubo k. Nat Cell Biol. 2023 Oct;25(10):1415-1425. doi: 10.1038/s41556-023-01240-7. Epub 2023 Oct 5. Nat Cell Biol. 2023. PMID: 37798545 Free PMC article.
432 results