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FoxM1 is up-regulated by obesity and stimulates beta-cell proliferation.
Davis DB, Lavine JA, Suhonen JI, Krautkramer KA, Rabaglia ME, Sperger JM, Fernandez LA, Yandell BS, Keller MP, Wang IM, Schadt EE, Attie AD. Davis DB, et al. Among authors: suhonen ji. Mol Endocrinol. 2010 Sep;24(9):1822-34. doi: 10.1210/me.2010-0082. Epub 2010 Jul 21. Mol Endocrinol. 2010. PMID: 20660304 Free PMC article.
Cholecystokinin is up-regulated in obese mouse islets and expands beta-cell mass by increasing beta-cell survival.
Lavine JA, Raess PW, Stapleton DS, Rabaglia ME, Suhonen JI, Schueler KL, Koltes JE, Dawson JA, Yandell BS, Samuelson LC, Beinfeld MC, Davis DB, Hellerstein MK, Keller MP, Attie AD. Lavine JA, et al. Among authors: suhonen ji. Endocrinology. 2010 Aug;151(8):3577-88. doi: 10.1210/en.2010-0233. Epub 2010 Jun 9. Endocrinology. 2010. PMID: 20534724 Free PMC article.