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FoxM1 is up-regulated by obesity and stimulates beta-cell proliferation.
Davis DB, Lavine JA, Suhonen JI, Krautkramer KA, Rabaglia ME, Sperger JM, Fernandez LA, Yandell BS, Keller MP, Wang IM, Schadt EE, Attie AD. Davis DB, et al. Among authors: schadt ee. Mol Endocrinol. 2010 Sep;24(9):1822-34. doi: 10.1210/me.2010-0082. Epub 2010 Jul 21. Mol Endocrinol. 2010. PMID: 20660304 Free PMC article.
Obesity and genetics regulate microRNAs in islets, liver, and adipose of diabetic mice.
Zhao E, Keller MP, Rabaglia ME, Oler AT, Stapleton DS, Schueler KL, Neto EC, Moon JY, Wang P, Wang IM, Lum PY, Ivanovska I, Cleary M, Greenawalt D, Tsang J, Choi YJ, Kleinhanz R, Shang J, Zhou YP, Howard AD, Zhang BB, Kendziorski C, Thornberry NA, Yandell BS, Schadt EE, Attie AD. Zhao E, et al. Among authors: schadt ee. Mamm Genome. 2009 Aug;20(8):476-85. doi: 10.1007/s00335-009-9217-2. Mamm Genome. 2009. PMID: 19727952 Free PMC article.
Liver and adipose expression associated SNPs are enriched for association to type 2 diabetes.
Zhong H, Beaulaurier J, Lum PY, Molony C, Yang X, Macneil DJ, Weingarth DT, Zhang B, Greenawalt D, Dobrin R, Hao K, Woo S, Fabre-Suver C, Qian S, Tota MR, Keller MP, Kendziorski CM, Yandell BS, Castro V, Attie AD, Kaplan LM, Schadt EE. Zhong H, et al. Among authors: schadt ee. PLoS Genet. 2010 May 6;6(5):e1000932. doi: 10.1371/journal.pgen.1000932. PLoS Genet. 2010. PMID: 20463879 Free PMC article.
A systems biology approach to drug discovery.
Zhu J, Zhang B, Schadt EE. Zhu J, et al. Among authors: schadt ee. Adv Genet. 2008;60:603-35. doi: 10.1016/S0065-2660(07)00421-X. Adv Genet. 2008. PMID: 18358334 Review.
422 results