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Genetic inactivation of the Fanconi anemia gene FANCC identified in the hepatocellular carcinoma cell line HuH-7 confers sensitivity towards DNA-interstrand crosslinking agents.
Palagyi A, Neveling K, Plinninger U, Ziesch A, Targosz BS, Denk GU, Ochs S, Rizzani A, Meier D, Thasler WE, Hanenberg H, De Toni EN, Bassermann F, Schäfer C, Göke B, Schindler D, Gallmeier E. Palagyi A, et al. Among authors: rizzani a. Mol Cancer. 2010 May 28;9:127. doi: 10.1186/1476-4598-9-127. Mol Cancer. 2010. PMID: 20509860 Free PMC article.