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Clinical trials of pharmacological therapies in acute heart failure syndromes: lessons learned and directions forward.
Felker GM, Pang PS, Adams KF, Cleland JG, Cotter G, Dickstein K, Filippatos GS, Fonarow GC, Greenberg BH, Hernandez AF, Khan S, Komajda M, Konstam MA, Liu PP, Maggioni AP, Massie BM, McMurray JJ, Mehra M, Metra M, O'Connell J, O'Connor CM, Pina IL, Ponikowski P, Sabbah HN, Teerlink JR, Udelson JE, Yancy CW, Zannad F, Gheorghiade M; International AHFS Working Group. Felker GM, et al. Among authors: cleland jg. Circ Heart Fail. 2010 Mar;3(2):314-25. doi: 10.1161/CIRCHEARTFAILURE.109.893222. Circ Heart Fail. 2010. PMID: 20233993 Review. No abstract available.
A description of the clinical characteristics at baseline of patients recruited into the Carvedilol or Metoprolol European Trial (COMET).
Cleland JG, Goode K, Erhardt L, Remme WJ, Charlesworth A, Poole-Wilson PA, Di Lenarda A, Hanrath P, Komajda M, Metra M, Swedberg K, Torp-Pedersen C; Carvedilol or Metoprolol European Trial Investigators. Cleland JG, et al. Cardiovasc Drugs Ther. 2004 Mar;18(2):139-52. doi: 10.1023/B:CARD.0000029032.46744.56. Cardiovasc Drugs Ther. 2004. PMID: 15162076 Clinical Trial.
Effects of metoprolol and carvedilol on cause-specific mortality and morbidity in patients with chronic heart failure--COMET.
Torp-Pedersen C, Poole-Wilson PA, Swedberg K, Cleland JG, Di Lenarda A, Hanrath P, Komajda M, Lutiger B, Metra M, Remme WJ, Scherhag A, Skene A; COMET Investigators. Torp-Pedersen C, et al. Among authors: cleland jg. Am Heart J. 2005 Feb;149(2):370-6. doi: 10.1016/j.ahj.2004.10.002. Am Heart J. 2005. PMID: 15846279 Clinical Trial.
Exchange of beta-blockers in heart failure patients. Experiences from the poststudy phase of COMET (the Carvedilol or Metoprolol European Trial).
Di Lenarda A, Remme WJ, Charlesworth A, Cleland JG, Lutiger B, Metra M, Komajda M, Torp-Pedersen C, Scherhag A, Swedberg K, Poole-Wilson PA; COMET investors. Di Lenarda A, et al. Among authors: cleland jg. Eur J Heart Fail. 2005 Jun;7(4):640-9. doi: 10.1016/j.ejheart.2004.09.010. Eur J Heart Fail. 2005. PMID: 15921806 Free article.
Influence of heart rate, blood pressure, and beta-blocker dose on outcome and the differences in outcome between carvedilol and metoprolol tartrate in patients with chronic heart failure: results from the COMET trial.
Metra M, Torp-Pedersen C, Swedberg K, Cleland JG, Di Lenarda A, Komajda M, Remme WJ, Lutiger B, Scherhag A, Lukas MA, Charlesworth A, Poole-Wilson PA. Metra M, et al. Among authors: cleland jg. Eur Heart J. 2005 Nov;26(21):2259-68. doi: 10.1093/eurheartj/ehi386. Epub 2005 Jul 21. Eur Heart J. 2005. PMID: 16040619 Clinical Trial.
Tezosentan in patients with acute heart failure: design of the Value of Endothelin Receptor Inhibition with Tezosentan in Acute heart failure Study (VERITAS).
Teerlink JR, McMurray JJ, Bourge RC, Cleland JG, Cotter G, Jondeau G, Krum H, Metra M, O'Connor CM, Parker JD, Torre-Amione G, Van Veldhuisen DJ, Frey A, Rainisio M, Kobrin I; VERITAS Investigators. Teerlink JR, et al. Among authors: cleland jg. Am Heart J. 2005 Jul;150(1):46-53. doi: 10.1016/j.ahj.2005.04.035. Am Heart J. 2005. PMID: 16084150
Under-utilization of evidence-based drug treatment in patients with heart failure is only partially explained by dissimilarity to patients enrolled in landmark trials: a report from the Euro Heart Survey on Heart Failure.
Lenzen MJ, Boersma E, Reimer WJ, Balk AH, Komajda M, Swedberg K, Follath F, Jimenez-Navarro M, Simoons ML, Cleland JG. Lenzen MJ, et al. Among authors: cleland jg. Eur Heart J. 2005 Dec;26(24):2706-13. doi: 10.1093/eurheartj/ehi499. Epub 2005 Sep 23. Eur Heart J. 2005. PMID: 16183692
1,134 results