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Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer.
Teschendorff AE, Menon U, Gentry-Maharaj A, Ramus SJ, Weisenberger DJ, Shen H, Campan M, Noushmehr H, Bell CG, Maxwell AP, Savage DA, Mueller-Holzner E, Marth C, Kocjan G, Gayther SA, Jones A, Beck S, Wagner W, Laird PW, Jacobs IJ, Widschwendter M. Teschendorff AE, et al. Among authors: laird pw. Genome Res. 2010 Apr;20(4):440-6. doi: 10.1101/gr.103606.109. Epub 2010 Mar 10. Genome Res. 2010. PMID: 20219944 Free PMC article.
DNA hypomethylation and ovarian cancer biology.
Widschwendter M, Jiang G, Woods C, Müller HM, Fiegl H, Goebel G, Marth C, Müller-Holzner E, Zeimet AG, Laird PW, Ehrlich M. Widschwendter M, et al. Among authors: laird pw. Cancer Res. 2004 Jul 1;64(13):4472-80. doi: 10.1158/0008-5472.CAN-04-0238. Cancer Res. 2004. PMID: 15231656
Analysis of repetitive element DNA methylation by MethyLight.
Weisenberger DJ, Campan M, Long TI, Kim M, Woods C, Fiala E, Ehrlich M, Laird PW. Weisenberger DJ, et al. Among authors: laird pw. Nucleic Acids Res. 2005 Dec 2;33(21):6823-36. doi: 10.1093/nar/gki987. Print 2005. Nucleic Acids Res. 2005. PMID: 16326863 Free PMC article.
CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer.
Weisenberger DJ, Siegmund KD, Campan M, Young J, Long TI, Faasse MA, Kang GH, Widschwendter M, Weener D, Buchanan D, Koh H, Simms L, Barker M, Leggett B, Levine J, Kim M, French AJ, Thibodeau SN, Jass J, Haile R, Laird PW. Weisenberger DJ, et al. Among authors: laird pw. Nat Genet. 2006 Jul;38(7):787-93. doi: 10.1038/ng1834. Epub 2006 Jun 25. Nat Genet. 2006. PMID: 16804544
331 results