Kitamura S - Search Results

1

Novel acyl coenzyme A (CoA): diacylglycerol acyltransferase-1 inhibitors: synthesis and biological activities of diacylethylenediamine derivatives.

Nakada Y, Aicher TD, Le Huerou Y, Turner T, Pratt SA, Gonzales SS, Boyd SA, Miki H, Yamamoto T, Yamaguchi H, Kato K, Kitamura S. Nakada Y, et al. Among authors: kitamura s. Bioorg Med Chem. 2010 Apr 1;18(7):2785-95. doi: 10.1016/j.bmc.2010.01.067. Epub 2010 Feb 4. Bioorg Med Chem. 2010. PMID: 20207151

2

A novel coenzyme A:diacylglycerol acyltransferase 1 inhibitor stimulates lipid metabolism in muscle and lowers weight in animal models of obesity.

Yamamoto T, Yamaguchi H, Miki H, Kitamura S, Nakada Y, Aicher TD, Pratt SA, Kato K. Yamamoto T, et al. Among authors: kitamura s. Eur J Pharmacol. 2011 Jan 15;650(2-3):663-72. doi: 10.1016/j.ejphar.2010.10.040. Epub 2010 Oct 29. Eur J Pharmacol. 2011. PMID: 21034741

3

Discovery, synthesis and biological evaluation of isoquinolones as novel and highly selective JNK inhibitors (1).

Asano Y, Kitamura S, Ohra T, Aso K, Igata H, Tamura T, Kawamoto T, Tanaka T, Sogabe S, Matsumoto S, Yamaguchi M, Kimura H, Itoh F. Asano Y, et al. Among authors: kitamura s. Bioorg Med Chem. 2008 Apr 15;16(8):4715-32. doi: 10.1016/j.bmc.2008.02.027. Epub 2008 Feb 13. Bioorg Med Chem. 2008. PMID: 18313304

4

Discovery, synthesis and biological evaluation of isoquinolones as novel and highly selective JNK inhibitors (2).

Asano Y, Kitamura S, Ohra T, Itoh F, Kajino M, Tamura T, Kaneko M, Ikeda S, Igata H, Kawamoto T, Sogabe S, Matsumoto S, Tanaka T, Yamaguchi M, Kimura H, Fukumoto S. Asano Y, et al. Among authors: kitamura s. Bioorg Med Chem. 2008 Apr 15;16(8):4699-714. doi: 10.1016/j.bmc.2008.02.028. Epub 2008 Feb 13. Bioorg Med Chem. 2008. PMID: 18313930

5

Potent dibasic GPIIb/IIIa antagonists with reduced prolongation of bleeding time: synthesis and pharmacological evaluation of 2-oxopiperazine derivatives.

Kitamura S, Fukushi H, Miyawaki T, Kawamura M, Konishi N, Terashita Z, Naka T. Kitamura S, et al. J Med Chem. 2001 Jul 19;44(15):2438-50. doi: 10.1021/jm0004345. J Med Chem. 2001. PMID: 11448226

6

Design, synthesis, and biological activity of potent and orally available G protein-coupled receptor 40 agonists.

Sasaki S, Kitamura S, Negoro N, Suzuki M, Tsujihata Y, Suzuki N, Santou T, Kanzaki N, Harada M, Tanaka Y, Kobayashi M, Tada N, Funami M, Tanaka T, Yamamoto Y, Fukatsu K, Yasuma T, Momose Y. Sasaki S, et al. Among authors: kitamura s. J Med Chem. 2011 Mar 10;54(5):1365-78. doi: 10.1021/jm101405t. Epub 2011 Feb 14. J Med Chem. 2011. PMID: 21319751

7

Discovery of novel serine palmitoyltransferase inhibitors as cancer therapeutic agents.

Kojima T, Asano Y, Kurasawa O, Hirata Y, Iwamura N, Wong TT, Saito B, Tanaka Y, Arai R, Yonemori K, Miyamoto Y, Sagiya Y, Yaguchi M, Shibata S, Mizutani A, Sano O, Adachi R, Satomi Y, Hirayama M, Aoyama K, Hiura Y, Kiba A, Kitamura S, Imamura S. Kojima T, et al. Among authors: kitamura s. Bioorg Med Chem. 2018 May 15;26(9):2452-2465. doi: 10.1016/j.bmc.2018.04.008. Epub 2018 Apr 4. Bioorg Med Chem. 2018. PMID: 29669694

8

Discovery of phenylpropanoic acid derivatives containing polar functionalities as potent and orally bioavailable G protein-coupled receptor 40 agonists for the treatment of type 2 diabetes.

Mikami S, Kitamura S, Negoro N, Sasaki S, Suzuki M, Tsujihata Y, Miyazaki T, Ito R, Suzuki N, Miyazaki J, Santou T, Kanzaki N, Funami M, Tanaka T, Yasuma T, Momose Y. Mikami S, et al. Among authors: kitamura s. J Med Chem. 2012 Apr 26;55(8):3756-76. doi: 10.1021/jm2016123. Epub 2012 Apr 11. J Med Chem. 2012. PMID: 22428944

9

New bronchodilators. 1. 1,5-Substituted 1H-imidazo[4,5-c]quinolin-4(5H)-ones.

Suzuki F, Kuroda T, Nakasato Y, Manabe H, Ohmori K, Kitamura S, Ichikawa S, Ohno T. Suzuki F, et al. Among authors: kitamura s. J Med Chem. 1992 Oct 30;35(22):4045-53. doi: 10.1021/jm00100a009. J Med Chem. 1992. PMID: 1331454

10

New bronchodilators. 3. Imidazo[4,5-c][1,8]naphthyridin-4(5H)-ones.

Suzuki F, Kuroda T, Kawakita T, Manabe H, Kitamura S, Ohmori K, Ichimura M, Kase H, Ichikawa S. Suzuki F, et al. Among authors: kitamura s. J Med Chem. 1992 Dec 25;35(26):4866-74. doi: 10.1021/jm00104a013. J Med Chem. 1992. PMID: 1479586

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