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The Tankyrase Inhibitor OM-153 Demonstrates Antitumor Efficacy and a Therapeutic Window in Mouse Models.
Brinch SA, Amundsen-Isaksen E, Espada S, Hammarström C, Aizenshtadt A, Olsen PA, Holmen L, Høyem M, Scholz H, Grødeland G, Sowa ST, Galera-Prat A, Lehtiö L, Meerts IATM, Leenders RGG, Wegert A, Krauss S, Waaler J. Brinch SA, et al. Among authors: lehtio l. Cancer Res Commun. 2022 Apr 20;2(4):233-245. doi: 10.1158/2767-9764.CRC-22-0027. eCollection 2022 Apr. Cancer Res Commun. 2022. PMID: 36873622 Free PMC article.
Zinc binding catalytic domain of human tankyrase 1.
Lehtiö L, Collins R, van den Berg S, Johansson A, Dahlgren LG, Hammarström M, Helleday T, Holmberg-Schiavone L, Karlberg T, Weigelt J. Lehtiö L, et al. J Mol Biol. 2008 May 23;379(1):136-45. doi: 10.1016/j.jmb.2008.03.058. Epub 2008 Apr 3. J Mol Biol. 2008. PMID: 18436240
The DEXD/H-box RNA helicase DDX19 is regulated by an {alpha}-helical switch.
Collins R, Karlberg T, Lehtiö L, Schütz P, van den Berg S, Dahlgren LG, Hammarström M, Weigelt J, Schüler H. Collins R, et al. Among authors: lehtio l. J Biol Chem. 2009 Apr 17;284(16):10296-300. doi: 10.1074/jbc.C900018200. Epub 2009 Feb 25. J Biol Chem. 2009. PMID: 19244245 Free PMC article.
Structural determination of functional domains in early B-cell factor (EBF) family of transcription factors reveals similarities to Rel DNA-binding proteins and a novel dimerization motif.
Siponen MI, Wisniewska M, Lehtiö L, Johansson I, Svensson L, Raszewski G, Nilsson L, Sigvardsson M, Berglund H. Siponen MI, et al. Among authors: lehtio l. J Biol Chem. 2010 Aug 20;285(34):25875-9. doi: 10.1074/jbc.C110.150482. Epub 2010 Jun 30. J Biol Chem. 2010. PMID: 20592035 Free PMC article.
99 results