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Synthesis and pharmacological evaluation of new 5-(cyclo)alkyl-5-phenyl- and 5-spiroimidazolidine-2,4-dione derivatives. Novel 5-HT1A receptor agonist with potential antidepressant and anxiolytic activity.
Czopek A, Byrtus H, Kołaczkowski M, Pawłowski M, Dybała M, Nowak G, Tatarczyńska E, Wesołowska A, Chojnacka-Wójcik E. Czopek A, et al. Among authors: tatarczynska e. Eur J Med Chem. 2010 Apr;45(4):1295-303. doi: 10.1016/j.ejmech.2009.11.053. Epub 2009 Dec 6. Eur J Med Chem. 2010. PMID: 20060623
The influence of substitution at aromatic part of 1,2,3,4-tetrahydroisoquinoline on in vitro and in vivo 5-HT(1A)/5-HT(2A) receptor activities of its 1-adamantoyloaminoalkyl derivatives.
Bojarski AJ, Mokrosz MJ, Minol SC, Kozioł A, Wesołowska A, Tatarczyńska E, Kłodzińska A, Chojnacka-Wójcik E. Bojarski AJ, et al. Among authors: tatarczynska e. Bioorg Med Chem. 2002 Jan;10(1):87-95. doi: 10.1016/s0968-0896(01)00236-x. Bioorg Med Chem. 2002. PMID: 11738610
Synthesis and pharmacological evaluation of new arylpiperazines. 3-[4-[4-(3-chlorophenyl)-1-piperazinyl]butyl]-quinazolidin-4-one - a dual serotonin 5-HT(1A)/5-HT(2A) receptor ligand with an anxiolytic-like activity.
Bojarski AJ, Kowalski P, Kowalska T, Duszyńska B, Charakchieva-Minol S, Tatarczyńska E, Kłodzińska A, Chojnacka-Wójcik E. Bojarski AJ, et al. Among authors: tatarczynska e. Bioorg Med Chem. 2002 Dec;10(12):3817-27. doi: 10.1016/s0968-0896(02)00349-8. Bioorg Med Chem. 2002. PMID: 12413835
Synthesis and 5-HT1A/5-HT2A receptor activity of new N-[3-(4-phenylpiperazin-1-yl)-propyl] derivatives of 3-spiro-cyclohexanepyrrolidine-2,5-dione and 3-spiro-beta-tetralonepyrrolidine-2,5-dione.
Obniska J, Pawłowski M, Kołaczkowski M, Czopek A, Duszyńska B, Klodzińska A, Tatarczyńska E, Chojnacka-Wójcik E. Obniska J, et al. Among authors: tatarczynska e. Pol J Pharmacol. 2003 Jul-Aug;55(4):553-7. Pol J Pharmacol. 2003. PMID: 14581713 Free article.
New arylpiperazine 5-HT(1A) receptor ligands containing the pyrimido[2,1-f]purine fragment: synthesis, in vitro, and in vivo pharmacological evaluation.
Jurczyk S, Kołaczkowski M, Maryniak E, Zajdel P, Pawłowski M, Tatarczyńska E, Kłodzińska A, Chojnacka-Wójcik E, Bojarski AJ, Charakchieva-Minol S, Duszyńska B, Nowak G, Maciag D. Jurczyk S, et al. Among authors: tatarczynska e. J Med Chem. 2004 May 6;47(10):2659-66. doi: 10.1021/jm030946u. J Med Chem. 2004. PMID: 15115407
Structure-intrinsic activity relationship studies in the group of 1-imido/amido substituted 4-(4-arylpiperazin-1-yl)cyclohexane derivatives; new, potent 5-HT1A receptor agents with anxiolytic- like activity.
Bojarski AJ, Paluchowska MH, Duszyńska B, Bugno R, Kłodzińska A, Tatarczyńska E, Chojnacka-Wójcik E. Bojarski AJ, et al. Among authors: tatarczynska e. Bioorg Med Chem. 2006 Mar 1;14(5):1391-402. doi: 10.1016/j.bmc.2005.09.060. Epub 2005 Nov 2. Bioorg Med Chem. 2006. PMID: 16266808
98 results