Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

101 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Circulating methylarginine levels and the decline in renal function in patients with chronic kidney disease are modulated by DDAH1 polymorphisms.
Caplin B, Nitsch D, Gill H, Hoefield R, Blackwell S, MacKenzie D, Cooper JA, Middleton RJ, Talmud PJ, Veitch P, Norman J, Wheeler DC, Leiper JM. Caplin B, et al. Among authors: leiper jm. Kidney Int. 2010 Mar;77(5):459-67. doi: 10.1038/ki.2009.463. Epub 2009 Dec 9. Kidney Int. 2010. PMID: 20010544 Free article.
Reduced Renal Methylarginine Metabolism Protects against Progressive Kidney Damage.
Tomlinson JA, Caplin B, Boruc O, Bruce-Cobbold C, Cutillas P, Dormann D, Faull P, Grossman RC, Khadayate S, Mas VR, Nitsch DD, Wang Z, Norman JT, Wilcox CS, Wheeler DC, Leiper J. Tomlinson JA, et al. J Am Soc Nephrol. 2015 Dec;26(12):3045-59. doi: 10.1681/ASN.2014030280. Epub 2015 Apr 8. J Am Soc Nephrol. 2015. PMID: 25855779 Free PMC article.
Alanine-glyoxylate aminotransferase-2 metabolizes endogenous methylarginines, regulates NO, and controls blood pressure.
Caplin B, Wang Z, Slaviero A, Tomlinson J, Dowsett L, Delahaye M, Salama A; International Consortium for Blood Pressure Genome-Wide Association Studies; Wheeler DC, Leiper J. Caplin B, et al. Arterioscler Thromb Vasc Biol. 2012 Dec;32(12):2892-900. doi: 10.1161/ATVBAHA.112.254078. Epub 2012 Sep 27. Arterioscler Thromb Vasc Biol. 2012. PMID: 23023372
Discovery of inhibitors of the pentein superfamily protein dimethylarginine dimethylaminohydrolase (DDAH), by virtual screening and hit analysis.
Hartzoulakis B, Rossiter S, Gill H, O'Hara B, Steinke E, Gane PJ, Hurtado-Guerrero R, Leiper JM, Vallance P, Rust JM, Selwood DL. Hartzoulakis B, et al. Among authors: leiper jm. Bioorg Med Chem Lett. 2007 Jul 15;17(14):3953-6. doi: 10.1016/j.bmcl.2007.04.095. Epub 2007 May 3. Bioorg Med Chem Lett. 2007. PMID: 17543521
Dimethylarginine dimethylaminohydrolase 2 regulates nitric oxide synthesis and hemodynamics and determines outcome in polymicrobial sepsis.
Lambden S, Kelly P, Ahmetaj-Shala B, Wang Z, Lee B, Nandi M, Torondel B, Delahaye M, Dowsett L, Piper S, Tomlinson J, Caplin B, Colman L, Boruc O, Slaviero A, Zhao L, Oliver E, Khadayate S, Singer M, Arrigoni F, Leiper J. Lambden S, et al. Arterioscler Thromb Vasc Biol. 2015 Jun;35(6):1382-92. doi: 10.1161/ATVBAHA.115.305278. Epub 2015 Apr 9. Arterioscler Thromb Vasc Biol. 2015. PMID: 25857313
Disruption of methylarginine metabolism impairs vascular homeostasis.
Leiper J, Nandi M, Torondel B, Murray-Rust J, Malaki M, O'Hara B, Rossiter S, Anthony S, Madhani M, Selwood D, Smith C, Wojciak-Stothard B, Rudiger A, Stidwill R, McDonald NQ, Vallance P. Leiper J, et al. Nat Med. 2007 Feb;13(2):198-203. doi: 10.1038/nm1543. Epub 2007 Feb 4. Nat Med. 2007. PMID: 17273169 Free article.
The DDAH-ADMA-NOS pathway.
Leiper JM. Leiper JM. Ther Drug Monit. 2005 Dec;27(6):744-6. doi: 10.1097/01.ftd.0000179849.42395.11. Ther Drug Monit. 2005. PMID: 16404814
101 results