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Novel cell death signaling pathways in neurotoxicity models of dopaminergic degeneration: relevance to oxidative stress and neuroinflammation in Parkinson's disease.
Kanthasamy A, Jin H, Mehrotra S, Mishra R, Kanthasamy A, Rana A. Kanthasamy A, et al. Among authors: rana a. Neurotoxicology. 2010 Sep;31(5):555-61. doi: 10.1016/j.neuro.2009.12.003. Epub 2009 Dec 11. Neurotoxicology. 2010. PMID: 20005250 Free PMC article. Review.
Parkinson's disease (PD) is a common neurodegenerative movement disorder characterized by extensive degeneration of dopaminergic neurons in the nigrostriatal system. ...Dr. Ajay Rana presented his recent work on the role of mixed lineage kinase-3 (MLK3) in neuroinfl …
Parkinson's disease (PD) is a common neurodegenerative movement disorder characterized by extensive degeneration of dopaminergic neur …
Emerging neurotoxic mechanisms in environmental factors-induced neurodegeneration.
Kanthasamy A, Jin H, Anantharam V, Sondarva G, Rangasamy V, Rana A, Kanthasamy A. Kanthasamy A, et al. Among authors: rana a. Neurotoxicology. 2012 Aug;33(4):833-7. doi: 10.1016/j.neuro.2012.01.011. Epub 2012 Feb 7. Neurotoxicology. 2012. PMID: 22342404 Free PMC article.
Exposure to environmental neurotoxic metals, pesticides and other chemicals is increasingly recognized as a key risk factor in the pathogenesis of chronic neurodegenerative disorders such as Parkinson's and Alzheimer's diseases. ...Dr. Ajay Rana provided evidence fo …
Exposure to environmental neurotoxic metals, pesticides and other chemicals is increasingly recognized as a key risk factor in the pa …
Histone hyperacetylation up-regulates protein kinase Cδ in dopaminergic neurons to induce cell death: relevance to epigenetic mechanisms of neurodegeneration in Parkinson disease.
Jin H, Kanthasamy A, Harischandra DS, Kondru N, Ghosh A, Panicker N, Anantharam V, Rana A, Kanthasamy AG. Jin H, et al. Among authors: rana a. J Biol Chem. 2014 Dec 12;289(50):34743-67. doi: 10.1074/jbc.M114.576702. Epub 2014 Oct 23. J Biol Chem. 2014. PMID: 25342743 Free PMC article.
Targeted toxicants to dopaminergic neuronal cell death.
Jin H, Kanthasamy A, Harischandra DS, Anantharam V, Rana A, Kanthasamy A. Jin H, et al. Among authors: rana a. Methods Mol Biol. 2015;1254:239-52. doi: 10.1007/978-1-4939-2152-2_18. Methods Mol Biol. 2015. PMID: 25431070
TRAF2-MLK3 interaction is essential for TNF-alpha-induced MLK3 activation.
Sondarva G, Kundu CN, Mehrotra S, Mishra R, Rangasamy V, Sathyanarayana P, Ray RS, Rana B, Rana A. Sondarva G, et al. Among authors: rana a, rana b. Cell Res. 2010 Jan;20(1):89-98. doi: 10.1038/cr.2009.125. Epub 2009 Nov 17. Cell Res. 2010. PMID: 19918265 Free PMC article.
Mixed-lineage kinase 3 phosphorylates prolyl-isomerase Pin1 to regulate its nuclear translocation and cellular function.
Rangasamy V, Mishra R, Sondarva G, Das S, Lee TH, Bakowska JC, Tzivion G, Malter JS, Rana B, Lu KP, Kanthasamy A, Rana A. Rangasamy V, et al. Among authors: rana a, rana b. Proc Natl Acad Sci U S A. 2012 May 22;109(21):8149-54. doi: 10.1073/pnas.1200804109. Epub 2012 May 7. Proc Natl Acad Sci U S A. 2012. PMID: 22566623 Free PMC article.
1,401 results