Glutathione supplementation potentiates hypoxic apoptosis by S-glutathionylation of p65-NFkappaB.
Qanungo S, Starke DW, Pai HV, Mieyal JJ, Nieminen AL.
Qanungo S, et al.
J Biol Chem. 2007 Jun 22;282(25):18427-18436. doi: 10.1074/jbc.M610934200. Epub 2007 Apr 27.
J Biol Chem. 2007.
PMID: 17468103
Free article.
In murine embryonic fibroblasts, N-acetyl-L-cysteine (NAC), a GSH generating agent, enhances hypoxic apoptosis by blocking the NFkappaB survival pathway (Qanungo, S., Wang, M., and Nieminen, A. L. (2004) J. Biol. Chem. 279, 50455-50464). ...In cells, knock-down of e …
In murine embryonic fibroblasts, N-acetyl-L-cysteine (NAC), a GSH generating agent, enhances hypoxic apoptosis by blocking the NFkappaB surv …