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TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei.
Shameer S, Logan-Klumpler FJ, Vinson F, Cottret L, Merlet B, Achcar F, Boshart M, Berriman M, Breitling R, Bringaud F, Bütikofer P, Cattanach AM, Bannerman-Chukualim B, Creek DJ, Crouch K, de Koning HP, Denise H, Ebikeme C, Fairlamb AH, Ferguson MA, Ginger ML, Hertz-Fowler C, Kerkhoven EJ, Mäser P, Michels PA, Nayak A, Nes DW, Nolan DP, Olsen C, Silva-Franco F, Smith TK, Taylor MC, Tielens AG, Urbaniak MD, van Hellemond JJ, Vincent IM, Wilkinson SR, Wyllie S, Opperdoes FR, Barrett MP, Jourdan F. Shameer S, et al. Among authors: ebikeme c. Nucleic Acids Res. 2015 Jan;43(Database issue):D637-44. doi: 10.1093/nar/gku944. Epub 2014 Oct 9. Nucleic Acids Res. 2015. PMID: 25300491 Free PMC article.
Cytosolic NADPH homeostasis in glucose-starved procyclic Trypanosoma brucei relies on malic enzyme and the pentose phosphate pathway fed by gluconeogenic flux.
Allmann S, Morand P, Ebikeme C, Gales L, Biran M, Hubert J, Brennand A, Mazet M, Franconi JM, Michels PA, Portais JC, Boshart M, Bringaud F. Allmann S, et al. Among authors: ebikeme c. J Biol Chem. 2013 Jun 21;288(25):18494-505. doi: 10.1074/jbc.M113.462978. Epub 2013 May 10. J Biol Chem. 2013. PMID: 23665470 Free PMC article.
The threonine degradation pathway of the Trypanosoma brucei procyclic form: the main carbon source for lipid biosynthesis is under metabolic control.
Millerioux Y, Ebikeme C, Biran M, Morand P, Bouyssou G, Vincent IM, Mazet M, Riviere L, Franconi JM, Burchmore RJ, Moreau P, Barrett MP, Bringaud F. Millerioux Y, et al. Among authors: ebikeme c. Mol Microbiol. 2013 Oct;90(1):114-29. doi: 10.1111/mmi.12351. Epub 2013 Aug 25. Mol Microbiol. 2013. PMID: 23899193 Free PMC article.
Ablation of succinate production from glucose metabolism in the procyclic trypanosomes induces metabolic switches to the glycerol 3-phosphate/dihydroxyacetone phosphate shuttle and to proline metabolism.
Ebikeme C, Hubert J, Biran M, Gouspillou G, Morand P, Plazolles N, Guegan F, Diolez P, Franconi JM, Portais JC, Bringaud F. Ebikeme C, et al. J Biol Chem. 2010 Oct 15;285(42):32312-24. doi: 10.1074/jbc.M110.124917. Epub 2010 Aug 11. J Biol Chem. 2010. PMID: 20702405 Free PMC article.
Transketolase in Trypanosoma brucei.
Stoffel SA, Alibu VP, Hubert J, Ebikeme C, Portais JC, Bringaud F, Schweingruber ME, Barrett MP. Stoffel SA, et al. Among authors: ebikeme c. Mol Biochem Parasitol. 2011 Sep;179(1):1-7. doi: 10.1016/j.molbiopara.2011.04.006. Epub 2011 May 12. Mol Biochem Parasitol. 2011. PMID: 21570429
ATP synthesis-coupled and -uncoupled acetate production from acetyl-CoA by mitochondrial acetate:succinate CoA-transferase and acetyl-CoA thioesterase in Trypanosoma.
Millerioux Y, Morand P, Biran M, Mazet M, Moreau P, Wargnies M, Ebikeme C, Deramchia K, Gales L, Portais JC, Boshart M, Franconi JM, Bringaud F. Millerioux Y, et al. Among authors: ebikeme c. J Biol Chem. 2012 May 18;287(21):17186-17197. doi: 10.1074/jbc.M112.355404. Epub 2012 Apr 2. J Biol Chem. 2012. PMID: 22474284 Free PMC article.
21 results