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KSR2 is an essential regulator of AMP kinase, energy expenditure, and insulin sensitivity.
Costanzo-Garvey DL, Pfluger PT, Dougherty MK, Stock JL, Boehm M, Chaika O, Fernandez MR, Fisher K, Kortum RL, Hong EG, Jun JY, Ko HJ, Schreiner A, Volle DJ, Treece T, Swift AL, Winer M, Chen D, Wu M, Leon LR, Shaw AS, McNeish J, Kim JK, Morrison DK, Tschöp MH, Lewis RE. Costanzo-Garvey DL, et al. Among authors: mcneish j. Cell Metab. 2009 Nov;10(5):366-78. doi: 10.1016/j.cmet.2009.09.010. Cell Metab. 2009. PMID: 19883615 Free PMC article.
Inducible, brain region-specific expression of a dominant negative mutant of c-Jun in transgenic mice decreases sensitivity to cocaine.
Peakman MC, Colby C, Perrotti LI, Tekumalla P, Carle T, Ulery P, Chao J, Duman C, Steffen C, Monteggia L, Allen MR, Stock JL, Duman RS, McNeish JD, Barrot M, Self DW, Nestler EJ, Schaeffer E. Peakman MC, et al. Among authors: mcneish jd. Brain Res. 2003 Apr 25;970(1-2):73-86. doi: 10.1016/s0006-8993(03)02230-3. Brain Res. 2003. PMID: 12706249
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