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The neuroprotective effect of erythropoietin in docetaxel-induced peripheral neuropathy causes no reduction of antitumor activity in 13762 adenocarcinoma-bearing rats.
Cervellini I, Bello E, Frapolli R, Porretta-Serapiglia C, Oggioni N, Canta A, Lombardi R, Camozzi F, Roglio I, Melcangi RC, D'incalci M, Lauria G, Ghezzi P, Cavaletti G, Bianchi R. Cervellini I, et al. Among authors: frapolli r. Neurotox Res. 2010 Aug;18(2):151-60. doi: 10.1007/s12640-009-9127-9. Epub 2009 Oct 30. Neurotox Res. 2010. PMID: 19876698
High-performance liquid chromatographic assay for the determination of the novel C-Seco-taxane derivative (IDN 5390) in mouse plasma.
Zaffaroni M, Frapolli R, Colombo T, Fruscio R, Bombardelli E, Morazzoni P, Riva A, D'Incalci M, Zucchetti M. Zaffaroni M, et al. Among authors: frapolli r. J Chromatogr B Analyt Technol Biomed Life Sci. 2002 Nov 15;780(1):93-8. doi: 10.1016/s1570-0232(02)00436-1. J Chromatogr B Analyt Technol Biomed Life Sci. 2002. PMID: 12383484
Fetal bovine serum, but not human serum, inhibits the in vitro cytotoxicity of ET-743 (Yondelis, trabectedin), an example of potential problems for extrapolation of active drug concentrations from in vitro studies.
Tognon G, Frapolli R, Zaffaroni M, Erba E, Zucchetti M, Faircloth GT, D'Incalci M. Tognon G, et al. Among authors: frapolli r. Cancer Chemother Pharmacol. 2004 Jan;53(1):89-90. doi: 10.1007/s00280-003-0704-y. Epub 2003 Oct 28. Cancer Chemother Pharmacol. 2004. PMID: 14586558 No abstract available.
Clindamycin-paclitaxel pharmacokinetic interaction in ovarian cancer patients.
Fruscio R, Lissoni AA, Frapolli R, Corso S, Mangioni C, D'Incalci M, Zucchetti M. Fruscio R, et al. Among authors: frapolli r. Cancer Chemother Pharmacol. 2006 Sep;58(3):319-25. doi: 10.1007/s00280-005-0160-y. Epub 2005 Dec 13. Cancer Chemother Pharmacol. 2006. PMID: 16362296 Clinical Trial.
Pharmacokinetics and metabolism in mice of IDN 5390 (13-(N-Boc-3-i-butylisoserinoyl)-C-7,8-seco-10-deacetylbaccatin III), a new oral c-seco-taxane derivative with antiangiogenic property effective on paclitaxel-resistant tumors.
Frapolli R, Marangon E, Zaffaroni M, Colombo T, Falcioni C, Bagnati R, Simone M, D'Incalci M, Manzotti C, Fontana G, Morazzoni P, Zucchetti M. Frapolli R, et al. Drug Metab Dispos. 2006 Dec;34(12):2028-35. doi: 10.1124/dmd.106.012153. Epub 2006 Sep 8. Drug Metab Dispos. 2006. PMID: 16963486
Biological properties of IDN5174, a new synthetic camptothecin with the open lactone ring.
Beretta GL, Petrangolini G, De Cesare M, Pratesi G, Perego P, Tinelli S, Tortoreto M, Zucchetti M, Frapolli R, Bello E, Manzotti C, Fontana G, Bombardelli E, Battaglia A, Samorì C, Zunino F. Beretta GL, et al. Among authors: frapolli r. Cancer Res. 2006 Nov 15;66(22):10976-82. doi: 10.1158/0008-5472.CAN-06-2158. Cancer Res. 2006. PMID: 17108136
G-quadruplex ligand RHPS4 potentiates the antitumor activity of camptothecins in preclinical models of solid tumors.
Leonetti C, Scarsella M, Riggio G, Rizzo A, Salvati E, D'Incalci M, Staszewsky L, Frapolli R, Stevens MF, Stoppacciaro A, Mottolese M, Antoniani B, Gilson E, Zupi G, Biroccio A. Leonetti C, et al. Among authors: frapolli r. Clin Cancer Res. 2008 Nov 15;14(22):7284-91. doi: 10.1158/1078-0432.CCR-08-0941. Clin Cancer Res. 2008. PMID: 19010844
82 results