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Sustained and specific in vitro inhibition of HIV-1 replication by a protease inhibitor encapsulated in gp120-targeted liposomes.
Clayton R, Ohagen A, Nicol F, Del Vecchio AM, Jonckers TH, Goethals O, Van Loock M, Michiels L, Grigsby J, Xu Z, Zhang YP, Gutshall LL, Cunningham M, Jiang H, Bola S, Sarisky RT, Hertogs K. Clayton R, et al. Among authors: van loock m. Antiviral Res. 2009 Nov;84(2):142-9. doi: 10.1016/j.antiviral.2009.08.003. Epub 2009 Aug 20. Antiviral Res. 2009. PMID: 19699239
Binding kinetics, uptake and intracellular accumulation of F105, an anti-gp120 human IgG1kappa monoclonal antibody, in HIV-1 infected cells.
Clayton R, Ohagen A, Goethals O, Smets A, Van Loock M, Michiels L, Kennedy-Johnston E, Cunningham M, Jiang H, Bola S, Gutshall L, Gunn G, Del Vecchio A, Sarisky R, Hallenberger S, Hertogs K. Clayton R, et al. Among authors: van loock m. J Virol Methods. 2007 Jan;139(1):17-23. doi: 10.1016/j.jviromet.2006.08.017. Epub 2006 Oct 10. J Virol Methods. 2007. PMID: 17034868
Resistance to raltegravir highlights integrase mutations at codon 148 in conferring cross-resistance to a second-generation HIV-1 integrase inhibitor.
Goethals O, Van Ginderen M, Vos A, Cummings MD, Van Der Borght K, Van Wesenbeeck L, Feyaerts M, Verheyen A, Smits V, Van Loock M, Hertogs K, Schols D, Clayton RF. Goethals O, et al. Among authors: van ginderen m, van wesenbeeck l, van loock m, van der borght k. Antiviral Res. 2011 Aug;91(2):167-76. doi: 10.1016/j.antiviral.2011.05.011. Epub 2011 Jun 12. Antiviral Res. 2011. PMID: 21669228
Biochemical screening assays to identify HIV-1 integrase inhibitors.
Clynhens M, Smets A, Vereycken I, Van Loock M, Clayton R, Meersseman G, Goethals O. Clynhens M, et al. Among authors: van loock m. Methods Mol Biol. 2013;1030:25-36. doi: 10.1007/978-1-62703-484-5_4. Methods Mol Biol. 2013. PMID: 23821258
Characterization of a dengue NS4B inhibitor originating from an HCV small molecule library.
Hernandez-Morales I, Geluykens P, Clynhens M, Strijbos R, Goethals O, Megens S, Verheyen N, Last S, McGowan D, Coesemans E, De Boeck B, Stoops B, Devogelaere B, Pauwels F, Vandyck K, Berke JM, Raboisson P, Simmen K, Lory P, Van Loock M. Hernandez-Morales I, et al. Among authors: van loock m. Antiviral Res. 2017 Nov;147:149-158. doi: 10.1016/j.antiviral.2017.10.011. Epub 2017 Oct 14. Antiviral Res. 2017. PMID: 29037976
A pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction.
Kaptein SJF, Goethals O, Kiemel D, Marchand A, Kesteleyn B, Bonfanti JF, Bardiot D, Stoops B, Jonckers THM, Dallmeier K, Geluykens P, Thys K, Crabbe M, Chatel-Chaix L, Münster M, Querat G, Touret F, de Lamballerie X, Raboisson P, Simmen K, Chaltin P, Bartenschlager R, Van Loock M, Neyts J. Kaptein SJF, et al. Among authors: van loock m. Nature. 2021 Oct;598(7881):504-509. doi: 10.1038/s41586-021-03990-6. Epub 2021 Oct 6. Nature. 2021. PMID: 34616043
Publisher Correction: A pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction.
Kaptein SJF, Goethals O, Kiemel D, Marchand A, Kesteleyn B, Bonfanti JF, Bardiot D, Stoops B, Jonckers THM, Dallmeier K, Geluykens P, Thys K, Crabbe M, Chatel-Chaix L, Münster M, Querat G, Touret F, de Lamballerie X, Raboisson P, Simmen K, Chaltin P, Bartenschlager R, Van Loock M, Neyts J. Kaptein SJF, et al. Among authors: van loock m. Nature. 2021 Nov;599(7883):E2. doi: 10.1038/s41586-021-04123-9. Nature. 2021. PMID: 34671169 No abstract available.
71 results