Froment MT - Search Results

1

Crystallographic snapshots of nonaged and aged conjugates of soman with acetylcholinesterase, and of a ternary complex of the aged conjugate with pralidoxime.

Sanson B, Nachon F, Colletier JP, Froment MT, Toker L, Greenblatt HM, Sussman JL, Ashani Y, Masson P, Silman I, Weik M. Sanson B, et al. Among authors: froment mt. J Med Chem. 2009 Dec 10;52(23):7593-603. doi: 10.1021/jm900433t. J Med Chem. 2009. PMID: 19642642

2

Reaction of cresyl saligenin phosphate, the organophosphorus agent implicated in aerotoxic syndrome, with human cholinesterases: mechanistic studies employing kinetics, mass spectrometry, and X-ray structure analysis.

Carletti E, Schopfer LM, Colletier JP, Froment MT, Nachon F, Weik M, Lockridge O, Masson P. Carletti E, et al. Among authors: froment mt. Chem Res Toxicol. 2011 Jun 20;24(6):797-808. doi: 10.1021/tx100447k. Epub 2011 Apr 18. Chem Res Toxicol. 2011. PMID: 21438623 Free PMC article.

3

Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation.

Carletti E, Li H, Li B, Ekström F, Nicolet Y, Loiodice M, Gillon E, Froment MT, Lockridge O, Schopfer LM, Masson P, Nachon F. Carletti E, et al. Among authors: froment mt. J Am Chem Soc. 2008 Nov 26;130(47):16011-20. doi: 10.1021/ja804941z. J Am Chem Soc. 2008. PMID: 18975951

4

Synthesis of 2-substituted beta-cyclodextrin derivatives with a hydrolytic activity against the organophosphorylester paraoxon.

Masurier N, Estour F, Froment MT, Lefèvre B, Debouzy JC, Brasme B, Masson P, Lafont O. Masurier N, et al. Among authors: froment mt. Eur J Med Chem. 2005 Jul;40(7):615-23. doi: 10.1016/j.ejmech.2005.02.008. Epub 2005 Apr 1. Eur J Med Chem. 2005. PMID: 15935896

5

Aging pathways for organophosphate-inhibited human butyrylcholinesterase, including novel pathways for isomalathion, resolved by mass spectrometry.

Li H, Schopfer LM, Nachon F, Froment MT, Masson P, Lockridge O. Li H, et al. Among authors: froment mt. Toxicol Sci. 2007 Nov;100(1):136-45. doi: 10.1093/toxsci/kfm215. Epub 2007 Aug 13. Toxicol Sci. 2007. PMID: 17698511

6

Aryl acylamidase activity of human serum albumin with o-nitrotrifluoroacetanilide as the substrate.

Masson P, Froment MT, Darvesh S, Schopfer LM, Lockridge O. Masson P, et al. Among authors: froment mt. J Enzyme Inhib Med Chem. 2007 Aug;22(4):463-9. doi: 10.1080/14756360701383932. J Enzyme Inhib Med Chem. 2007. PMID: 17847714

7

Organophosphate hydrolases as catalytic bioscavengers of organophosphorus nerve agents.

Trovaslet-Leroy M, Musilova L, Renault F, Brazzolotto X, Misik J, Novotny L, Froment MT, Gillon E, Loiodice M, Verdier L, Masson P, Rochu D, Jun D, Nachon F. Trovaslet-Leroy M, et al. Among authors: froment mt. Toxicol Lett. 2011 Sep 25;206(1):14-23. doi: 10.1016/j.toxlet.2011.05.1041. Epub 2011 Jun 12. Toxicol Lett. 2011. PMID: 21683774

8

Mutant of Bungarus fasciatus acetylcholinesterase with low affinity and low hydrolase activity toward organophosphorus esters.

Poyot T, Nachon F, Froment MT, Loiodice M, Wieseler S, Schopfer LM, Lockridge O, Masson P. Poyot T, et al. Among authors: froment mt. Biochim Biophys Acta. 2006 Sep;1764(9):1470-8. doi: 10.1016/j.bbapap.2006.07.008. Epub 2006 Aug 4. Biochim Biophys Acta. 2006. PMID: 16962835

9

Binding and hydrolysis of soman by human serum albumin.

Li B, Nachon F, Froment MT, Verdier L, Debouzy JC, Brasme B, Gillon E, Schopfer LM, Lockridge O, Masson P. Li B, et al. Among authors: froment mt. Chem Res Toxicol. 2008 Feb;21(2):421-31. doi: 10.1021/tx700339m. Epub 2007 Dec 29. Chem Res Toxicol. 2008. PMID: 18163544

10

Kinetic analysis of effector modulation of butyrylcholinesterase-catalysed hydrolysis of acetanilides and homologous esters.

Masson P, Froment MT, Gillon E, Nachon F, Lockridge O, Schopfer LM. Masson P, et al. Among authors: froment mt. FEBS J. 2008 May;275(10):2617-31. doi: 10.1111/j.1742-4658.2008.06409.x. Epub 2008 Apr 15. FEBS J. 2008. PMID: 18422653 Free article.

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