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The impact of molecular variants, crystallization conditions and the space group on ligand-protein complexes: a case study on bacterial phosphotriesterase.
Dym O, Aggarwal N, Ashani Y, Leader H, Albeck S, Unger T, Hamer-Rogotner S, Silman I, Tawfik DS, Sussman JL. Dym O, et al. Among authors: ashani y. Acta Crystallogr D Struct Biol. 2023 Nov 1;79(Pt 11):992-1009. doi: 10.1107/S2059798323007672. Epub 2023 Oct 20. Acta Crystallogr D Struct Biol. 2023. PMID: 37860961 Free PMC article.
Design of a stable human acid-β-glucosidase: towards improved Gaucher disease therapy and mutation classification.
Pokorna S, Khersonsky O, Lipsh-Sokolik R, Goldenzweig A, Nielsen R, Ashani Y, Peleg Y, Unger T, Albeck S, Dym O, Tirosh A, Tarayra R, Hocquemiller M, Laufer R, Ben-Dor S, Silman I, Sussman JL, Fleishman SJ, Futerman AH. Pokorna S, et al. Among authors: ashani y. FEBS J. 2023 Jul;290(13):3383-3399. doi: 10.1111/febs.16758. Epub 2023 Mar 23. FEBS J. 2023. PMID: 36808692
Utilization of diverse organophosphorus pollutants by marine bacteria.
Despotović D, Aharon E, Trofimyuk O, Dubovetskyi A, Cherukuri KP, Ashani Y, Eliason O, Sperfeld M, Leader H, Castelli A, Fumagalli L, Savidor A, Levin Y, Longo LM, Segev E, Tawfik DS. Despotović D, et al. Among authors: ashani y. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2203604119. doi: 10.1073/pnas.2203604119. Epub 2022 Aug 2. Proc Natl Acad Sci U S A. 2022. PMID: 35917352 Free PMC article.
Automated Design of Efficient and Functionally Diverse Enzyme Repertoires.
Khersonsky O, Lipsh R, Avizemer Z, Ashani Y, Goldsmith M, Leader H, Dym O, Rogotner S, Trudeau DL, Prilusky J, Amengual-Rigo P, Guallar V, Tawfik DS, Fleishman SJ. Khersonsky O, et al. Among authors: ashani y. Mol Cell. 2018 Oct 4;72(1):178-186.e5. doi: 10.1016/j.molcel.2018.08.033. Epub 2018 Sep 27. Mol Cell. 2018. PMID: 30270109 Free PMC article.
Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability.
Goldenzweig A, Goldsmith M, Hill SE, Gertman O, Laurino P, Ashani Y, Dym O, Unger T, Albeck S, Prilusky J, Lieberman RL, Aharoni A, Silman I, Sussman JL, Tawfik DS, Fleishman SJ. Goldenzweig A, et al. Among authors: ashani y. Mol Cell. 2018 Apr 19;70(2):380. doi: 10.1016/j.molcel.2018.03.035. Mol Cell. 2018. PMID: 29677494 Free PMC article. No abstract available.
94 results