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Page 1
Proteasomal and genetic inactivation of the NF1 tumor suppressor in gliomagenesis.
McGillicuddy LT, Fromm JA, Hollstein PE, Kubek S, Beroukhim R, De Raedt T, Johnson BW, Williams SM, Nghiemphu P, Liau LM, Cloughesy TF, Mischel PS, Parret A, Seiler J, Moldenhauer G, Scheffzek K, Stemmer-Rachamimov AO, Sawyers CL, Brennan C, Messiaen L, Mellinghoff IK, Cichowski K. McGillicuddy LT, et al. Among authors: de raedt t. Cancer Cell. 2009 Jul 7;16(1):44-54. doi: 10.1016/j.ccr.2009.05.009. Cancer Cell. 2009. PMID: 19573811 Free PMC article.
Molecular pathogenesis of multiple gastrointestinal stromal tumors in NF1 patients.
Maertens O, Prenen H, Debiec-Rychter M, Wozniak A, Sciot R, Pauwels P, De Wever I, Vermeesch JR, de Raedt T, De Paepe A, Speleman F, van Oosterom A, Messiaen L, Legius E. Maertens O, et al. Among authors: de paepe a, de raedt t, de wever i. Hum Mol Genet. 2006 Mar 15;15(6):1015-23. doi: 10.1093/hmg/ddl016. Epub 2006 Feb 6. Hum Mol Genet. 2006. PMID: 16461335
Comprehensive NF1 screening on cultured Schwann cells from neurofibromas.
Maertens O, Brems H, Vandesompele J, De Raedt T, Heyns I, Rosenbaum T, De Schepper S, De Paepe A, Mortier G, Janssens S, Speleman F, Legius E, Messiaen L. Maertens O, et al. Among authors: de paepe a, de schepper s, de raedt t. Hum Mutat. 2006 Oct;27(10):1030-40. doi: 10.1002/humu.20389. Hum Mutat. 2006. PMID: 16941471
An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-kappaB.
Min J, Zaslavsky A, Fedele G, McLaughlin SK, Reczek EE, De Raedt T, Guney I, Strochlic DE, Macconaill LE, Beroukhim R, Bronson RT, Ryeom S, Hahn WC, Loda M, Cichowski K. Min J, et al. Among authors: de raedt t. Nat Med. 2010 Mar;16(3):286-94. doi: 10.1038/nm.2100. Epub 2010 Feb 14. Nat Med. 2010. PMID: 20154697 Free PMC article.
Atypical neurofibromas in neurofibromatosis type 1 are premalignant tumors.
Beert E, Brems H, Daniëls B, De Wever I, Van Calenbergh F, Schoenaers J, Debiec-Rychter M, Gevaert O, De Raedt T, Van Den Bruel A, de Ravel T, Cichowski K, Kluwe L, Mautner V, Sciot R, Legius E. Beert E, et al. Among authors: de ravel t, de raedt t, de wever i. Genes Chromosomes Cancer. 2011 Dec;50(12):1021-32. doi: 10.1002/gcc.20921. Epub 2011 Aug 24. Genes Chromosomes Cancer. 2011. PMID: 21987445
The RasGAP gene, RASAL2, is a tumor and metastasis suppressor.
McLaughlin SK, Olsen SN, Dake B, De Raedt T, Lim E, Bronson RT, Beroukhim R, Polyak K, Brown M, Kuperwasser C, Cichowski K. McLaughlin SK, et al. Among authors: de raedt t. Cancer Cell. 2013 Sep 9;24(3):365-78. doi: 10.1016/j.ccr.2013.08.004. Cancer Cell. 2013. PMID: 24029233 Free PMC article.
The activation of the WNT signaling pathway is a Hallmark in neurofibromatosis type 1 tumorigenesis.
Luscan A, Shackleford G, Masliah-Planchon J, Laurendeau I, Ortonne N, Varin J, Lallemand F, Leroy K, Dumaine V, Hivelin M, Borderie D, De Raedt T, Valeyrie-Allanore L, Larousserie F, Terris B, Lantieri L, Vidaud M, Vidaud D, Wolkenstein P, Parfait B, Bièche I, Massaad C, Pasmant E. Luscan A, et al. Among authors: de raedt t. Clin Cancer Res. 2014 Jan 15;20(2):358-71. doi: 10.1158/1078-0432.CCR-13-0780. Epub 2013 Nov 11. Clin Cancer Res. 2014. PMID: 24218515
34 results