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Translocator protein (18 kD) as target for anxiolytics without benzodiazepine-like side effects.
Rupprecht R, Rammes G, Eser D, Baghai TC, Schüle C, Nothdurfter C, Troxler T, Gentsch C, Kalkman HO, Chaperon F, Uzunov V, McAllister KH, Bertaina-Anglade V, La Rochelle CD, Tuerck D, Floesser A, Kiese B, Schumacher M, Landgraf R, Holsboer F, Kucher K. Rupprecht R, et al. Among authors: schumacher m. Science. 2009 Jul 24;325(5939):490-3. doi: 10.1126/science.1175055. Epub 2009 Jun 18. Science. 2009. PMID: 19541954 Clinical Trial.
A novel dual mode-of-action anti-hyperalgesic compound in rats which is neuroprotective and promotes neuroregeneration.
Bloms-Funke P, Schumacher M, Liu S, Su D, Li J, Liere P, Rupprecht R, Nothdurfter C, Bahrenberg G, Christoph T, Habermann C, Kneip C, Schröder W, Tzschentke TM, Saunders D. Bloms-Funke P, et al. Among authors: schumacher m. Eur J Pharmacol. 2022 May 15;923:174935. doi: 10.1016/j.ejphar.2022.174935. Epub 2022 Apr 2. Eur J Pharmacol. 2022. PMID: 35378102
1,971 results