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Identification of [4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)-2-pyrimidinyl] amines and ethers as potent and selective cyclooxygenase-2 inhibitors.
Bioorg Med Chem Lett. 2009 Aug 1;19(15):4504-8. doi: 10.1016/j.bmcl.2009.02.085. Epub 2009 Feb 26.
Bioorg Med Chem Lett. 2009.
PMID: 19520573
Identification of 2,3-diaryl-pyrazolo[1,5-b]pyridazines as potent and selective cyclooxygenase-2 inhibitors.
Beswick P, Bingham S, Bountra C, Brown T, Browning K, Campbell I, Chessell I, Clayton N, Collins S, Corfield J, Guntrip S, Haslam C, Lambeth P, Lucas F, Mathews N, Murkit G, Naylor A, Pegg N, Pickup E, Player H, Price H, Stevens A, Stratton S, Wiseman J.
Beswick P, et al.
Bioorg Med Chem Lett. 2004 Nov 1;14(21):5445-8. doi: 10.1016/j.bmcl.2004.07.089.
Bioorg Med Chem Lett. 2004.
PMID: 15454242
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Identification and optimisation of a novel series of pyrimidine based cyclooxygenase-2 (COX-2) inhibitors. Utilisation of a biotransformation approach.
Beswick PJ, Blackaby AP, Bountra C, Brown T, Browning K, Campbell IB, Corfield J, Gleave RJ, Guntrip SB, Hall RM, Hindley S, Lambeth PF, Lucas F, Mathews N, Naylor A, Player H, Price HS, Sidebottom PJ, Taylor NL, Webb G, Wiseman J.
Beswick PJ, et al.
Bioorg Med Chem Lett. 2009 Aug 1;19(15):4509-14. doi: 10.1016/j.bmcl.2009.02.089. Epub 2009 Feb 27.
Bioorg Med Chem Lett. 2009.
PMID: 19523822
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Optimization of novel acyl pyrrolidine inhibitors of hepatitis C virus RNA-dependent RNA polymerase leading to a development candidate.
Slater MJ, Amphlett EM, Andrews DM, Bravi G, Burton G, Cheasty AG, Corfield JA, Ellis MR, Fenwick RH, Fernandes S, Guidetti R, Haigh D, Hartley CD, Howes PD, Jackson DL, Jarvest RL, Lovegrove VL, Medhurst KJ, Parry NR, Price H, Shah P, Singh OM, Stocker R, Thommes P, Wilkinson C, Wonacott A.
Slater MJ, et al. Among authors: corfield ja.
J Med Chem. 2007 Mar 8;50(5):897-900. doi: 10.1021/jm061207r. Epub 2007 Feb 2.
J Med Chem. 2007.
PMID: 17269759
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Asymmetric synthesis of an N-acylpyrrolidine for inhibition of HCV polymerase.
Agbodjan AA, Cooley BE, Copley RC, Corfield JA, Flanagan RC, Glover BN, Guidetti R, Haigh D, Howes PD, Jackson MM, Matsuoka RT, Medhurst KJ, Millar A, Sharp MJ, Slater MJ, Toczko JF, Xie S.
Agbodjan AA, et al. Among authors: corfield ja.
J Org Chem. 2008 Apr 18;73(8):3094-102. doi: 10.1021/jo800062c. Epub 2008 Mar 22.
J Org Chem. 2008.
PMID: 18358046
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Measuring and predicting Delta(vap)H298 values of ionic liquids.
Deyko A, Lovelock KR, Corfield JA, Taylor AW, Gooden PN, Villar-Garcia IJ, Licence P, Jones RG, Krasovskiy VG, Chernikova EA, Kustov LM.
Deyko A, et al. Among authors: corfield ja.
Phys Chem Chem Phys. 2009 Oct 14;11(38):8544-55. doi: 10.1039/b908209c. Epub 2009 Jul 27.
Phys Chem Chem Phys. 2009.
PMID: 19774286
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Vaporisation of a dicationic ionic liquid.
Lovelock KR, Deyko A, Corfield JA, Gooden PN, Licence P, Jones RG.
Lovelock KR, et al. Among authors: corfield ja.
Chemphyschem. 2009 Feb 2;10(2):337-40. doi: 10.1002/cphc.200800690.
Chemphyschem. 2009.
PMID: 19067443
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Pyrrolidinium-based ionic liquids. 1-Butyl-1-methyl pyrrolidinium dicyanoamide: thermochemical measurement, mass spectrometry, and ab initio calculations.
Emel'yanenko VN, Verevkin SP, Heintz A, Corfield JA, Deyko A, Lovelock KR, Licence P, Jones RG.
Emel'yanenko VN, et al. Among authors: corfield ja.
J Phys Chem B. 2008 Sep 18;112(37):11734-42. doi: 10.1021/jp803238t. Epub 2008 Aug 26.
J Phys Chem B. 2008.
PMID: 18729398
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