Fröhling S - Search Results

1

Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cells.

Scholl C, Fröhling S, Dunn IF, Schinzel AC, Barbie DA, Kim SY, Silver SJ, Tamayo P, Wadlow RC, Ramaswamy S, Döhner K, Bullinger L, Sandy P, Boehm JS, Root DE, Jacks T, Hahn WC, Gilliland DG. Scholl C, et al. Among authors: frohling s. Cell. 2009 May 29;137(5):821-34. doi: 10.1016/j.cell.2009.03.017. Cell. 2009. PMID: 19490892 Free article.

2

Development of a real-time RT-PCR assay for the quantification of the most frequent MLL/AF9 fusion types resulting from translocation t(9;11)(p22;q23) in acute myeloid leukemia.

Scholl C, Breitinger H, Schlenk RF, Döhner H, Fröhling S, Döhner K; AML Study Group Ulm. Scholl C, et al. Among authors: frohling s. Genes Chromosomes Cancer. 2003 Nov;38(3):274-80. doi: 10.1002/gcc.10284. Genes Chromosomes Cancer. 2003. PMID: 14506704

3

Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis.

Levine RL, Wadleigh M, Cools J, Ebert BL, Wernig G, Huntly BJ, Boggon TJ, Wlodarska I, Clark JJ, Moore S, Adelsperger J, Koo S, Lee JC, Gabriel S, Mercher T, D'Andrea A, Fröhling S, Döhner K, Marynen P, Vandenberghe P, Mesa RA, Tefferi A, Griffin JD, Eck MJ, Sellers WR, Meyerson M, Golub TR, Lee SJ, Gilliland DG. Levine RL, et al. Among authors: frohling s. Cancer Cell. 2005 Apr;7(4):387-97. doi: 10.1016/j.ccr.2005.03.023. Cancer Cell. 2005. PMID: 15837627 Free article.

4

Mutant nucleophosmin (NPM1) predicts favorable prognosis in younger adults with acute myeloid leukemia and normal cytogenetics: interaction with other gene mutations.

Döhner K, Schlenk RF, Habdank M, Scholl C, Rücker FG, Corbacioglu A, Bullinger L, Fröhling S, Döhner H. Döhner K, et al. Among authors: frohling s. Blood. 2005 Dec 1;106(12):3740-6. doi: 10.1182/blood-2005-05-2164. Epub 2005 Jul 28. Blood. 2005. PMID: 16051734 Free article.

5

Genetics of myeloid malignancies: pathogenetic and clinical implications.

Fröhling S, Scholl C, Gilliland DG, Levine RL. Fröhling S, et al. J Clin Oncol. 2005 Sep 10;23(26):6285-95. doi: 10.1200/JCO.2005.05.010. J Clin Oncol. 2005. PMID: 16155011 Review.

6

The prognostic value of MLL-AF9 detection in patients with t(9;11)(p22;q23)-positive acute myeloid leukemia.

Scholl C, Schlenk RF, Eiwen K, Döhner H, Fröhling S, Döhner K; AML Study Group. Scholl C, et al. Among authors: frohling s. Haematologica. 2005 Dec;90(12):1626-34. Haematologica. 2005. PMID: 16330435

7

Rare occurrence of the JAK2 V617F mutation in AML subtypes M5, M6, and M7.

Fröhling S, Lipka DB, Kayser S, Scholl C, Schlenk RF, Döhner H, Gilliland DG, Levine RL, Döhner K. Fröhling S, et al. Blood. 2006 Feb 1;107(3):1242-3. doi: 10.1182/blood-2005-09-3644. Blood. 2006. PMID: 16434499 Free PMC article. No abstract available.

8

JAK2T875N is a novel activating mutation that results in myeloproliferative disease with features of megakaryoblastic leukemia in a murine bone marrow transplantation model.

Mercher T, Wernig G, Moore SA, Levine RL, Gu TL, Fröhling S, Cullen D, Polakiewicz RD, Bernard OA, Boggon TJ, Lee BH, Gilliland DG. Mercher T, et al. Among authors: frohling s. Blood. 2006 Oct 15;108(8):2770-9. doi: 10.1182/blood-2006-04-014712. Epub 2006 Jun 27. Blood. 2006. PMID: 16804112 Free PMC article.

9

Cdx4 dysregulates Hox gene expression and generates acute myeloid leukemia alone and in cooperation with Meis1a in a murine model.

Bansal D, Scholl C, Fröhling S, McDowell E, Lee BH, Döhner K, Ernst P, Davidson AJ, Daley GQ, Zon LI, Gilliland DG, Huntly BJ. Bansal D, et al. Among authors: frohling s. Proc Natl Acad Sci U S A. 2006 Nov 7;103(45):16924-9. doi: 10.1073/pnas.0604579103. Epub 2006 Oct 26. Proc Natl Acad Sci U S A. 2006. PMID: 17068127 Free PMC article.

10

The homeobox gene CDX2 is aberrantly expressed in most cases of acute myeloid leukemia and promotes leukemogenesis.

Scholl C, Bansal D, Döhner K, Eiwen K, Huntly BJ, Lee BH, Rücker FG, Schlenk RF, Bullinger L, Döhner H, Gilliland DG, Fröhling S. Scholl C, et al. Among authors: frohling s. J Clin Invest. 2007 Apr;117(4):1037-48. doi: 10.1172/JCI30182. Epub 2007 Mar 8. J Clin Invest. 2007. PMID: 17347684 Free PMC article.

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