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Comparative study of inhibition at multiple stages of amyloid-beta self-assembly provides mechanistic insight.
Mol Pharmacol. 2009 Aug;76(2):405-13. doi: 10.1124/mol.109.055301. Epub 2009 May 29.
Mol Pharmacol. 2009.
PMID: 19483107
Soluble aggregates of the amyloid-beta protein activate endothelial monolayers for adhesion and subsequent transmigration of monocyte cells.
Gonzalez-Velasquez FJ, Moss MA.
Gonzalez-Velasquez FJ, et al.
J Neurochem. 2008 Jan;104(2):500-13. doi: 10.1111/j.1471-4159.2007.04988.x. Epub 2007 Oct 22.
J Neurochem. 2008.
PMID: 17953673
Free article.
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Soluble aggregates of the amyloid-beta protein selectively stimulate permeability in human brain microvascular endothelial monolayers.
Gonzalez-Velasquez FJ, Kotarek JA, Moss MA.
Gonzalez-Velasquez FJ, et al.
J Neurochem. 2008 Oct;107(2):466-77. doi: 10.1111/j.1471-4159.2008.05618.x. Epub 2008 Sep 16.
J Neurochem. 2008.
PMID: 18702666
Free PMC article.
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Inhibition of amyloid-β aggregation by coumarin analogs can be manipulated by functionalization of the aromatic center.
Soto-Ortega DD, Murphy BP, Gonzalez-Velasquez FJ, Wilson KA, Xie F, Wang Q, Moss MA.
Soto-Ortega DD, et al. Among authors: gonzalez velasquez fj.
Bioorg Med Chem. 2011 Apr 15;19(8):2596-602. doi: 10.1016/j.bmc.2011.03.010. Epub 2011 Mar 12.
Bioorg Med Chem. 2011.
PMID: 21458277
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Soluble aggregates of the amyloid-beta peptide are trapped by serum albumin to enhance amyloid-beta activation of endothelial cells.
Reyes Barcelo AA, Gonzalez-Velasquez FJ, Moss MA.
Reyes Barcelo AA, et al. Among authors: gonzalez velasquez fj.
J Biol Eng. 2009 Apr 27;3:5. doi: 10.1186/1754-1611-3-5.
J Biol Eng. 2009.
PMID: 19397812
Free PMC article.
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Activation of brain endothelium by soluble aggregates of the amyloid-β protein involves nuclear factor-κB.
Gonzalez-Velasquez F, Reed JW, Fuseler JW, Matherly EE, Kotarek JA, Soto-Ortega DD, Moss MA.
Gonzalez-Velasquez F, et al.
Curr Alzheimer Res. 2011 Feb;8(1):81-94. doi: 10.2174/156720511794604606.
Curr Alzheimer Res. 2011.
PMID: 21143156
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