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The novel NO-donating compound GIT-27NO inhibits in vivo growth of human prostate cancer cells and prevents murine immunoinflammatory hepatitis.
Donia M, Mijatovic S, Maksimovic-Ivanic D, Miljkovic D, Mangano K, Tumino S, Biondi A, Basile F, Al-Abed Y, Stosic-Grujicic S, Nicoletti F. Donia M, et al. Among authors: miljkovic d. Eur J Pharmacol. 2009 Aug 1;615(1-3):228-33. doi: 10.1016/j.ejphar.2009.04.069. Epub 2009 May 14. Eur J Pharmacol. 2009. PMID: 19446546
In vitro and in vivo anticancer action of Saquinavir-NO, a novel nitric oxide-derivative of the protease inhibitor saquinavir, on hormone resistant prostate cancer cells.
Donia M, Maksimovic-Ivanic D, Mijatovic S, Mojic M, Miljkovic D, Timotijevic G, Fagone P, Caponnetto S, Al-Abed Y, McCubrey J, Stosic-Grujicic S, Nicoletti F. Donia M, et al. Among authors: miljkovic d. Cell Cycle. 2011 Feb 1;10(3):492-9. doi: 10.4161/cc.10.3.14727. Epub 2011 Feb 1. Cell Cycle. 2011. PMID: 21270522
A potent immunomodulatory compound, (S,R)-3-Phenyl-4,5-dihydro-5-isoxazole acetic acid, prevents spontaneous and accelerated forms of autoimmune diabetes in NOD mice and inhibits the immunoinflammatory diabetes induced by multiple low doses of streptozotocin in CBA/H mice.
Stosic-Grujicic S, Cvetkovic I, Mangano K, Fresta M, Maksimovic-Ivanic D, Harhaji L, Popadic D, Momcilovic M, Miljkovic D, Kim J, Al-Abed Y, Nicoletti F. Stosic-Grujicic S, et al. Among authors: miljkovic d. J Pharmacol Exp Ther. 2007 Mar;320(3):1038-49. doi: 10.1124/jpet.106.109272. Epub 2006 Dec 5. J Pharmacol Exp Ther. 2007. PMID: 17148780
Anticancer properties of the novel nitric oxide-donating compound (S,R)-3-phenyl-4,5-dihydro-5-isoxazole acetic acid-nitric oxide in vitro and in vivo.
Maksimovic-Ivanic D, Mijatovic S, Harhaji L, Miljkovic D, Dabideen D, Fan Cheng K, Mangano K, Malaponte G, Al-Abed Y, Libra M, Garotta G, Nicoletti F, Stosic-Grujicic S. Maksimovic-Ivanic D, et al. Among authors: miljkovic d. Mol Cancer Ther. 2008 Mar;7(3):510-20. doi: 10.1158/1535-7163.MCT-07-2037. Mol Cancer Ther. 2008. PMID: 18347138
Novel nitric oxide-donating compound (S,R)-3-phenyl-4,5-dihydro-5-isoxazole acetic acid-nitric oxide (GIT-27NO) induces p53 mediated apoptosis in human A375 melanoma cells.
Mijatovic S, Maksimovic-Ivanic D, Mojic M, Malaponte G, Libra M, Cardile V, Miljkovic D, Harhaji L, Dabideen D, Cheng KF, Bevelacqua Y, Donia M, Garotta G, Al-Abed Y, Stosic-Grujicic S, Nicoletti F. Mijatovic S, et al. Among authors: miljkovic d. Nitric Oxide. 2008 Sep;19(2):177-83. doi: 10.1016/j.niox.2008.04.004. Epub 2008 May 19. Nitric Oxide. 2008. PMID: 18460348
The antitumor properties of a nontoxic, nitric oxide-modified version of saquinavir are independent of Akt.
Maksimovic-Ivanic D, Mijatovic S, Miljkovic D, Harhaji-Trajkovic L, Timotijevic G, Mojic M, Dabideen D, Cheng KF, McCubrey JA, Mangano K, Al-Abed Y, Libra M, Garotta G, Stosic-Grujicic S, Nicoletti F. Maksimovic-Ivanic D, et al. Among authors: miljkovic d. Mol Cancer Ther. 2009 May;8(5):1169-78. doi: 10.1158/1535-7163.MCT-08-0998. Epub 2009 May 5. Mol Cancer Ther. 2009. PMID: 19417156
Induction of caspase-independent apoptotic-like cell death of mouse mammary tumor TA3Ha cells in vitro and reduction of their lethality in vivo by the novel chemotherapeutic agent GIT-27NO.
Mijatovic S, Maksimovic-Ivanic D, Timotijevic G, Miljkovic D, Donia M, Libra M, Coco M, McCubrey J, Al-Abed Y, Korac A, Stosic-Grujicic S, Nicoletti F. Mijatovic S, et al. Among authors: miljkovic d. Free Radic Biol Med. 2010 Apr 15;48(8):1090-9. doi: 10.1016/j.freeradbiomed.2010.01.026. Epub 2010 Jan 28. Free Radic Biol Med. 2010. PMID: 20114073
Therapeutic potential of nitric oxide-modified drugs in colon cancer cells.
Mojic M, Mijatovic S, Maksimovic-Ivanic D, Miljkovic D, Stosic-Grujicic S, Stankovic M, Mangano K, Travali S, Donia M, Fagone P, Zocca MB, Al-Abed Y, McCubrey JA, Nicoletti F. Mojic M, et al. Among authors: miljkovic d. Mol Pharmacol. 2012 Oct;82(4):700-10. doi: 10.1124/mol.112.077842. Epub 2012 Jul 13. Mol Pharmacol. 2012. PMID: 22798453
The NO-modified HIV protease inhibitor as a valuable drug for hematological malignancies: Role of p70S6K.
Maksimovic-Ivanic D, Mojic M, Bulatovic M, Radojkovic M, Kuzmanovic M, Ristic S, Stosic-Grujicic S, Miljkovic D, Cavalli E, Libra M, Fagone P, McCubrey J, Nicoletti F, Mijatovic S. Maksimovic-Ivanic D, et al. Among authors: miljkovic d. Leuk Res. 2015 Oct;39(10):1088-95. doi: 10.1016/j.leukres.2015.06.013. Epub 2015 Jun 28. Leuk Res. 2015. PMID: 26220866
In vitro, ex vivo and in vivo immunopharmacological activities of the isoxazoline compound VGX-1027: modulation of cytokine synthesis and prevention of both organ-specific and systemic autoimmune diseases in murine models.
Stojanovic I, Cuzzocrea S, Mangano K, Mazzon E, Miljkovic D, Wang M, Donia M, Al Abed Y, Kim J, Nicoletti F, Stosic-Grujicic S, Claesson M. Stojanovic I, et al. Among authors: miljkovic d. Clin Immunol. 2007 Jun;123(3):311-23. doi: 10.1016/j.clim.2007.03.004. Epub 2007 Apr 20. Clin Immunol. 2007. PMID: 17449326
206 results