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Caveolin-1 (P132L), a common breast cancer mutation, confers mammary cell invasiveness and defines a novel stem cell/metastasis-associated gene signature.
Bonuccelli G, Casimiro MC, Sotgia F, Wang C, Liu M, Katiyar S, Zhou J, Dew E, Capozza F, Daumer KM, Minetti C, Milliman JN, Alpy F, Rio MC, Tomasetto C, Mercier I, Flomenberg N, Frank PG, Pestell RG, Lisanti MP. Bonuccelli G, et al. Among authors: minetti c. Am J Pathol. 2009 May;174(5):1650-62. doi: 10.2353/ajpath.2009.080648. Am J Pathol. 2009. PMID: 19395651 Free PMC article.
Loss of caveolin-3 induces a lactogenic microenvironment that is protective against mammary tumor formation.
Sotgia F, Casimiro MC, Bonuccelli G, Liu M, Whitaker-Menezes D, Er O, Daumer KM, Mercier I, Witkiewicz AK, Minetti C, Capozza F, Gormley M, Quong AA, Rui H, Frank PG, Milliman JN, Knudsen ES, Zhou J, Wang C, Pestell RG, Lisanti MP. Sotgia F, et al. Among authors: minetti c. Am J Pathol. 2009 Feb;174(2):613-29. doi: 10.2353/ajpath.2009.080653. Am J Pathol. 2009. PMID: 19164602 Free PMC article.
Caveolin-1-/- null mammary stromal fibroblasts share characteristics with human breast cancer-associated fibroblasts.
Sotgia F, Del Galdo F, Casimiro MC, Bonuccelli G, Mercier I, Whitaker-Menezes D, Daumer KM, Zhou J, Wang C, Katiyar S, Xu H, Bosco E, Quong AA, Aronow B, Witkiewicz AK, Minetti C, Frank PG, Jimenez SA, Knudsen ES, Pestell RG, Lisanti MP. Sotgia F, et al. Among authors: minetti c. Am J Pathol. 2009 Mar;174(3):746-61. doi: 10.2353/ajpath.2009.080658. Am J Pathol. 2009. PMID: 19234134 Free PMC article.
Phosphofructokinase muscle-specific isoform requires caveolin-3 expression for plasma membrane recruitment and caveolar targeting: implications for the pathogenesis of caveolin-related muscle diseases.
Sotgia F, Bonuccelli G, Minetti C, Woodman SE, Capozza F, Kemp RG, Scherer PE, Lisanti MP. Sotgia F, et al. Among authors: minetti c. Am J Pathol. 2003 Dec;163(6):2619-34. doi: 10.1016/S0002-9440(10)63616-4. Am J Pathol. 2003. PMID: 14633633 Free PMC article.
Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue.
Whitaker-Menezes D, Martinez-Outschoorn UE, Flomenberg N, Birbe RC, Witkiewicz AK, Howell A, Pavlides S, Tsirigos A, Ertel A, Pestell RG, Broda P, Minetti C, Lisanti MP, Sotgia F. Whitaker-Menezes D, et al. Among authors: minetti c. Cell Cycle. 2011 Dec 1;10(23):4047-64. doi: 10.4161/cc.10.23.18151. Epub 2011 Dec 1. Cell Cycle. 2011. PMID: 22134189 Free PMC article.
378 results