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Caveolin-1 (P132L), a common breast cancer mutation, confers mammary cell invasiveness and defines a novel stem cell/metastasis-associated gene signature.
Bonuccelli G, Casimiro MC, Sotgia F, Wang C, Liu M, Katiyar S, Zhou J, Dew E, Capozza F, Daumer KM, Minetti C, Milliman JN, Alpy F, Rio MC, Tomasetto C, Mercier I, Flomenberg N, Frank PG, Pestell RG, Lisanti MP. Bonuccelli G, et al. Among authors: frank pg. Am J Pathol. 2009 May;174(5):1650-62. doi: 10.2353/ajpath.2009.080648. Am J Pathol. 2009. PMID: 19395651 Free PMC article.
Caveolin-1/3 double-knockout mice are viable, but lack both muscle and non-muscle caveolae, and develop a severe cardiomyopathic phenotype.
Park DS, Woodman SE, Schubert W, Cohen AW, Frank PG, Chandra M, Shirani J, Razani B, Tang B, Jelicks LA, Factor SM, Weiss LM, Tanowitz HB, Lisanti MP. Park DS, et al. Among authors: frank pg. Am J Pathol. 2002 Jun;160(6):2207-17. doi: 10.1016/S0002-9440(10)61168-6. Am J Pathol. 2002. PMID: 12057923 Free PMC article.
Caveolin, caveolae, and endothelial cell function.
Frank PG, Woodman SE, Park DS, Lisanti MP. Frank PG, et al. Arterioscler Thromb Vasc Biol. 2003 Jul 1;23(7):1161-8. doi: 10.1161/01.ATV.0000070546.16946.3A. Epub 2003 Apr 10. Arterioscler Thromb Vasc Biol. 2003. PMID: 12689915 Review.
91 results