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Caveolin-1 (P132L), a common breast cancer mutation, confers mammary cell invasiveness and defines a novel stem cell/metastasis-associated gene signature.
Bonuccelli G, Casimiro MC, Sotgia F, Wang C, Liu M, Katiyar S, Zhou J, Dew E, Capozza F, Daumer KM, Minetti C, Milliman JN, Alpy F, Rio MC, Tomasetto C, Mercier I, Flomenberg N, Frank PG, Pestell RG, Lisanti MP. Bonuccelli G, et al. Among authors: capozza f. Am J Pathol. 2009 May;174(5):1650-62. doi: 10.2353/ajpath.2009.080648. Am J Pathol. 2009. PMID: 19395651 Free PMC article.
Stromal and epithelial caveolin-1 both confer a protective effect against mammary hyperplasia and tumorigenesis: Caveolin-1 antagonizes cyclin D1 function in mammary epithelial cells.
Williams TM, Sotgia F, Lee H, Hassan G, Di Vizio D, Bonuccelli G, Capozza F, Mercier I, Rui H, Pestell RG, Lisanti MP. Williams TM, et al. Among authors: capozza f. Am J Pathol. 2006 Nov;169(5):1784-801. doi: 10.2353/ajpath.2006.060590. Am J Pathol. 2006. PMID: 17071600 Free PMC article.
Loss of caveolin-3 induces a lactogenic microenvironment that is protective against mammary tumor formation.
Sotgia F, Casimiro MC, Bonuccelli G, Liu M, Whitaker-Menezes D, Er O, Daumer KM, Mercier I, Witkiewicz AK, Minetti C, Capozza F, Gormley M, Quong AA, Rui H, Frank PG, Milliman JN, Knudsen ES, Zhou J, Wang C, Pestell RG, Lisanti MP. Sotgia F, et al. Among authors: capozza f. Am J Pathol. 2009 Feb;174(2):613-29. doi: 10.2353/ajpath.2009.080653. Am J Pathol. 2009. PMID: 19164602 Free PMC article.
Role of cholesterol in the development and progression of breast cancer.
Llaverias G, Danilo C, Mercier I, Daumer K, Capozza F, Williams TM, Sotgia F, Lisanti MP, Frank PG. Llaverias G, et al. Among authors: capozza f. Am J Pathol. 2011 Jan;178(1):402-12. doi: 10.1016/j.ajpath.2010.11.005. Epub 2010 Dec 23. Am J Pathol. 2011. PMID: 21224077 Free PMC article.
Phosphofructokinase muscle-specific isoform requires caveolin-3 expression for plasma membrane recruitment and caveolar targeting: implications for the pathogenesis of caveolin-related muscle diseases.
Sotgia F, Bonuccelli G, Minetti C, Woodman SE, Capozza F, Kemp RG, Scherer PE, Lisanti MP. Sotgia F, et al. Among authors: capozza f. Am J Pathol. 2003 Dec;163(6):2619-34. doi: 10.1016/S0002-9440(10)63616-4. Am J Pathol. 2003. PMID: 14633633 Free PMC article.
36 results