Chong WK - Search Results

1

Synthesis of novel nitric oxide (NO)-releasing esters of timolol.

Chiroli V, Batugo MR, Biondi S, Bonfanti A, Brambilla S, Gale DC, Li L, Miglietta D, Nicoli F, Prasanna GA, Ronchetti D, Vernier WF, Chong WK. Chiroli V, et al. Among authors: chong wk. Bioorg Med Chem Lett. 2009 May 15;19(10):2785-8. doi: 10.1016/j.bmcl.2009.03.111. Epub 2009 Mar 27. Bioorg Med Chem Lett. 2009. PMID: 19361986

2

Nitric oxide-donating carbonic anhydrase inhibitors for the treatment of open-angle glaucoma.

Steele RM, Benedini F, Biondi S, Borghi V, Carzaniga L, Impagnatiello F, Miglietta D, Chong WK, Rajapakse R, Cecchi A, Temperini C, Supuran CT. Steele RM, et al. Among authors: chong wk. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6565-70. doi: 10.1016/j.bmcl.2009.10.036. Epub 2009 Oct 13. Bioorg Med Chem Lett. 2009. PMID: 19854054

3

A novel nitric oxide releasing prostaglandin analog, NCX 125, reduces intraocular pressure in rabbit, dog, and primate models of glaucoma.

Borghi V, Bastia E, Guzzetta M, Chiroli V, Toris CB, Batugo MR, Carreiro ST, Chong WK, Gale DC, Kucera DJ, Jia L, Prasanna G, Ongini E, Krauss AH, Impagnatiello F. Borghi V, et al. Among authors: chong wk. J Ocul Pharmacol Ther. 2010 Apr;26(2):125-32. doi: 10.1089/jop.2009.0120. J Ocul Pharmacol Ther. 2010. PMID: 20415621

4

A dual acting compound with latanoprost amide and nitric oxide releasing properties, shows ocular hypotensive effects in rabbits and dogs.

Impagnatiello F, Borghi V, Gale DC, Batugo M, Guzzetta M, Brambilla S, Carreiro ST, Chong WK, Prasanna G, Chiroli V, Ongini E, Krauss AH. Impagnatiello F, et al. Among authors: chong wk. Exp Eye Res. 2011 Sep;93(3):243-9. doi: 10.1016/j.exer.2011.02.006. Epub 2011 Feb 26. Exp Eye Res. 2011. PMID: 21356209

5

Ocular hypotensive activity of BOL-303259-X, a nitric oxide donating prostaglandin F2α agonist, in preclinical models.

Krauss AH, Impagnatiello F, Toris CB, Gale DC, Prasanna G, Borghi V, Chiroli V, Chong WK, Carreiro ST, Ongini E. Krauss AH, et al. Among authors: chong wk. Exp Eye Res. 2011 Sep;93(3):250-5. doi: 10.1016/j.exer.2011.03.001. Epub 2011 Mar 9. Exp Eye Res. 2011. PMID: 21396362

6

Thioether benzenesulfonamide inhibitors of carbonic anhydrases II and IV: structure-based drug design, synthesis, and biological evaluation.

Vernier W, Chong W, Rewolinski D, Greasley S, Pauly T, Shaw M, Dinh D, Ferre RA, Meador JW 3rd, Nukui S, Ornelas M, Paz RL, Reyner E. Vernier W, et al. Bioorg Med Chem. 2010 May 1;18(9):3307-19. doi: 10.1016/j.bmc.2010.03.014. Epub 2010 Mar 11. Bioorg Med Chem. 2010. PMID: 20363633

7

Synthesis and antiinflammatory activity of novel 12 beta-substituted analogues of betamethasone.

Avery MA, Detre G, Yasuda D, Chao WR, Tanabe M, Crowe D, Peters R, Chong WK. Avery MA, et al. Among authors: chong wk. J Med Chem. 1990 Jul;33(7):1852-8. doi: 10.1021/jm00169a004. J Med Chem. 1990. PMID: 2362263

8

Structure-activity relationships of the antimalarial agent artemisinin. 1. Synthesis and comparative molecular field analysis of C-9 analogs of artemisinin and 10-deoxoartemisinin.

Avery MA, Gao F, Chong WK, Mehrotra S, Milhous WK. Avery MA, et al. Among authors: chong wk. J Med Chem. 1993 Dec 24;36(26):4264-75. doi: 10.1021/jm00078a017. J Med Chem. 1993. PMID: 8277509

9

Structure-activity relationships of the antimalarial agent artemisinin. 2. Effect of heteroatom substitution at O-11: synthesis and bioassay of N-alkyl-11-aza-9-desmethylartemisinins.

Avery MA, Bonk JD, Chong WK, Mehrotra S, Miller R, Milhous W, Goins DK, Venkatesan S, Wyandt C, Khan I, et al. Avery MA, et al. Among authors: chong wk. J Med Chem. 1995 Dec 22;38(26):5038-44. doi: 10.1021/jm00026a011. J Med Chem. 1995. PMID: 8544180

10

Steroidal silicon side-chain analogues as potential antifertility agents.

Peters RH, Crowe DF, Tanabe M, Avery MA, Chong WK. Peters RH, et al. Among authors: chong wk. J Med Chem. 1987 Apr;30(4):646-52. doi: 10.1021/jm00387a011. J Med Chem. 1987. PMID: 3560158

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