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Synthesis of novel nitric oxide (NO)-releasing esters of timolol.
Chiroli V, Batugo MR, Biondi S, Bonfanti A, Brambilla S, Gale DC, Li L, Miglietta D, Nicoli F, Prasanna GA, Ronchetti D, Vernier WF, Chong WK. Chiroli V, et al. Among authors: brambilla s. Bioorg Med Chem Lett. 2009 May 15;19(10):2785-8. doi: 10.1016/j.bmcl.2009.03.111. Epub 2009 Mar 27. Bioorg Med Chem Lett. 2009. PMID: 19361986
Repeated Dosing with NCX1404, a Nitric Oxide-Donating Pregabalin, Re-establishes Normal Nociceptive Responses in Mice with Streptozotocin-Induced Painful Diabetic Neuropathy.
Varani K, Vincenzi F, Targa M, Ravani A, Bastia E, Storoni L, Brambilla S, Almirante N, Impagnatiello F. Varani K, et al. Among authors: brambilla s. J Pharmacol Exp Ther. 2016 May;357(2):240-7. doi: 10.1124/jpet.115.230193. Epub 2016 Feb 23. J Pharmacol Exp Ther. 2016. PMID: 26907623
NCX 1741, a Novel Nitric Oxide-Donating Phosphodiesterase-5 Inhibitor, Exerts Rapid and Long-Lasting Intraocular Pressure-Lowering in Cynomolgus Monkeys.
Bastia E, Toris C, Bukowski JM, Brambilla S, Galli C, Almirante N, Bergamini MVW, Lucarini L, Navratil T, Impagnatiello F. Bastia E, et al. Among authors: brambilla s. J Ocul Pharmacol Ther. 2021 May;37(4):215-222. doi: 10.1089/jop.2020.0126. Epub 2021 Feb 15. J Ocul Pharmacol Ther. 2021. PMID: 33595367
Identification of RC-33 as a potent and selective σ1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. Part 2: g-scale synthesis, physicochemical characterization and in vitro metabolic stability.
Rossi D, Marra A, Picconi P, Serra M, Catenacci L, Sorrenti M, Laurini E, Fermeglia M, Pricl S, Brambilla S, Almirante N, Peviani M, Curti D, Collina S. Rossi D, et al. Among authors: brambilla s. Bioorg Med Chem. 2013 May 1;21(9):2577-86. doi: 10.1016/j.bmc.2013.02.029. Epub 2013 Feb 26. Bioorg Med Chem. 2013. PMID: 23498917
NCX 667, a Novel Nitric Oxide Donor, Lowers Intraocular Pressure in Rabbits, Dogs, and Non-Human Primates and Enhances TGFβ2-Induced Outflow in HTM/HSC Constructs.
Bastia E, Toris CB, Brambilla S, Galli C, Almirante N, Bergamini MVW, Masini E, Sgambellone S, Unser AM, Ahmed F, Torrejon KY, Navratil T, Impagnatiello F. Bastia E, et al. Among authors: brambilla s. Invest Ophthalmol Vis Sci. 2021 Mar 1;62(3):17. doi: 10.1167/iovs.62.3.17. Invest Ophthalmol Vis Sci. 2021. PMID: 33704360 Free PMC article.
88 results