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Leoligin, the major lignan from Edelweiss, inhibits intimal hyperplasia of venous bypass grafts.
Reisinger U, Schwaiger S, Zeller I, Messner B, Stigler R, Wiedemann D, Mayr T, Seger C, Schachner T, Dirsch VM, Vollmar AM, Bonatti JO, Stuppner H, Laufer G, Bernhard D. Reisinger U, et al. Among authors: zeller i. Cardiovasc Res. 2009 Jun 1;82(3):542-9. doi: 10.1093/cvr/cvp059. Epub 2009 Feb 19. Cardiovasc Res. 2009. PMID: 19228707 Free PMC article.
Lead contributes to arterial intimal hyperplasia through nuclear factor erythroid 2-related factor-mediated endothelial interleukin 8 synthesis and subsequent invasion of smooth muscle cells.
Zeller I, Knoflach M, Seubert A, Kreutmayer SB, Stelzmüller ME, Wallnoefer E, Blunder S, Frotschnig S, Messner B, Willeit J, Debbage P, Wick G, Kiechl S, Laufer G, Bernhard D. Zeller I, et al. Arterioscler Thromb Vasc Biol. 2010 Sep;30(9):1733-40. doi: 10.1161/ATVBAHA.110.211011. Epub 2010 Jul 1. Arterioscler Thromb Vasc Biol. 2010. PMID: 20595649
Ursolic acid causes DNA-damage, p53-mediated, mitochondria- and caspase-dependent human endothelial cell apoptosis, and accelerates atherosclerotic plaque formation in vivo.
Messner B, Zeller I, Ploner C, Frotschnig S, Ringer T, Steinacher-Nigisch A, Ritsch A, Laufer G, Huck C, Bernhard D. Messner B, et al. Among authors: zeller i. Atherosclerosis. 2011 Dec;219(2):402-8. doi: 10.1016/j.atherosclerosis.2011.05.025. Epub 2011 Jun 23. Atherosclerosis. 2011. PMID: 21703625
Characteristics of TAV- and BAV-associated thoracic aortic aneurysms--smooth muscle cell biology, expression profiling, and histological analyses.
Blunder S, Messner B, Aschacher T, Zeller I, Türkcan A, Wiedemann D, Andreas M, Blüschke G, Laufer G, Schachner T, Bernhard D. Blunder S, et al. Among authors: zeller i. Atherosclerosis. 2012 Feb;220(2):355-61. doi: 10.1016/j.atherosclerosis.2011.11.035. Epub 2011 Nov 28. Atherosclerosis. 2012. PMID: 22178424
Targeted gene expression analyses and immunohistology suggest a pro-proliferative state in tricuspid aortic valve-, and senescence and viral infections in bicuspid aortic valve-associated thoracic aortic aneurysms.
Blunder S, Messner B, Scharinger B, Doppler C, Zeller I, Zierer A, Laufer G, Bernhard D. Blunder S, et al. Among authors: zeller i. Atherosclerosis. 2018 Apr;271:111-119. doi: 10.1016/j.atherosclerosis.2018.02.007. Epub 2018 Feb 5. Atherosclerosis. 2018. PMID: 29486395 Free article.
Tylophorine reduces protein biosynthesis and rapidly decreases cyclin D1, inhibiting vascular smooth muscle cell proliferation in vitro and in organ culture.
Joa H, Blažević T, Grojer C, Zeller I, Heiss EH, Atanasov AG, Feldler I, Gruzdaitis P, Czaloun C, Proksch P, Messner B, Bernhard D, Dirsch VM. Joa H, et al. Among authors: zeller i. Phytomedicine. 2019 Jul;60:152938. doi: 10.1016/j.phymed.2019.152938. Epub 2019 Apr 23. Phytomedicine. 2019. PMID: 31078367
35 results