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Development of the first ultra-potent "capsaicinoid" agonist at transient receptor potential vanilloid type 1 (TRPV1) channels and its therapeutic potential.
Appendino G, De Petrocellis L, Trevisani M, Minassi A, Daddario N, Moriello AS, Gazzieri D, Ligresti A, Campi B, Fontana G, Pinna C, Geppetti P, Di Marzo V. Appendino G, et al. Among authors: trevisani m. J Pharmacol Exp Ther. 2005 Feb;312(2):561-70. doi: 10.1124/jpet.104.074864. Epub 2004 Sep 8. J Pharmacol Exp Ther. 2005. PMID: 15356216
Cigarette smoke-induced neurogenic inflammation is mediated by alpha,beta-unsaturated aldehydes and the TRPA1 receptor in rodents.
Andrè E, Campi B, Materazzi S, Trevisani M, Amadesi S, Massi D, Creminon C, Vaksman N, Nassini R, Civelli M, Baraldi PG, Poole DP, Bunnett NW, Geppetti P, Patacchini R. Andrè E, et al. Among authors: trevisani m. J Clin Invest. 2008 Jul;118(7):2574-82. doi: 10.1172/JCI34886. J Clin Invest. 2008. PMID: 18568077 Free PMC article.
Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents.
Nassini R, Materazzi S, Andrè E, Sartiani L, Aldini G, Trevisani M, Carnini C, Massi D, Pedretti P, Carini M, Cerbai E, Preti D, Villetti G, Civelli M, Trevisan G, Azzari C, Stokesberry S, Sadofsky L, McGarvey L, Patacchini R, Geppetti P. Nassini R, et al. Among authors: trevisani m. FASEB J. 2010 Dec;24(12):4904-16. doi: 10.1096/fj.10-162438. Epub 2010 Aug 18. FASEB J. 2010. PMID: 20720158
Ethanol elicits and potentiates nociceptor responses via the vanilloid receptor-1.
Trevisani M, Smart D, Gunthorpe MJ, Tognetto M, Barbieri M, Campi B, Amadesi S, Gray J, Jerman JC, Brough SJ, Owen D, Smith GD, Randall AD, Harrison S, Bianchi A, Davis JB, Geppetti P. Trevisani M, et al. Nat Neurosci. 2002 Jun;5(6):546-51. doi: 10.1038/nn0602-852. Nat Neurosci. 2002. PMID: 11992116
Antitussive activity of iodo-resiniferatoxin in guinea pigs.
Trevisani M, Milan A, Gatti R, Zanasi A, Harrison S, Fontana G, Morice AH, Geppetti P. Trevisani M, et al. Thorax. 2004 Sep;59(9):769-72. doi: 10.1136/thx.2003.012930. Thorax. 2004. PMID: 15333853 Free PMC article.
120 results